基于"形气神一体观"从"心-脑-肾轴"初探多发性骨髓瘤的病机OA
Preliminary Exploration of the Pathogenesis of Multiple Myeloma from the Perspective of the"Heart-Brain-Kidney Axis"Based on the Concept of"The Unit of Form,Qi,and Spirit"
多发性骨髓瘤是一种浆细胞恶性增殖性疾病,属中医"骨痹"范畴,其病位不仅在肾,还与心、脑密切相关.中医学认为形气神是生命的三大要素,三者相互关联,又相互影响,是一个统一的整体;而心、脑、肾与形气神紧密相连,体现了人体生理功能的整体性与协调性.本文基于"形气神一体观",提出"心-脑-肾轴"失衡是多发性骨髓瘤的核心病机,脑肾不济、心肾不交、心脑不通导致形损、气乱、神衰,并根据现代医学研究进一步论证多发性骨髓瘤与"心-脑-肾轴"的相关性.
Multiple myeloma is a malignant proliferative disease of plasma cells,which falls into the catego-ry of"Bone Bi Syndrome"in traditional Chinese medicine.Its pathological sites are not only in the kidney,but also closely related to the heart and brain.Traditional Chinese medicine believes that Form,Qi,and spirit are the three essential elements of life,which are interrelated and mutually influential,forming a unified whole.The heart,brain,and kidney are closely interconnected with the form,Qi,and spirit,reflecting the integrity and coordination of the human physiological functions.Based on the concept of"The Unit of Form,Qi,and spirit",this article proposes that the imbalance of the"heart-brain-kidney axis"is the core pathogenesis of multiple myeloma.Insufficiency of the brain and kidney,disharmony between heart kidney,and obstruction between heart and brain can lead to morphological damage,Qi disorder,and mental decline.And modern medical re-search further demonstrates the correlation between multiple myeloma and the"heart-brain-kidney axis".
宋玉;王海宏;徐彦煜;赵继梅;王定雪;田杰
贵州中医药大学,贵州 贵阳 550025贵州中医药大学,贵州 贵阳 550025贵州中医药大学,贵州 贵阳 550025贵州中医药大学,贵州 贵阳 550025贵州中医药大学第一附属医院,贵州 贵阳 550001贵州中医药大学第一附属医院,贵州 贵阳 550001||黔东南州中医医院,贵州 凯里 556000
医药卫生
形气神整体观念心-脑-肾轴多发性骨髓瘤病机
Form,Qi and spiritintegrity conceptheart-brain-kidney axismultiple myelomapathogen-esis
《贵州中医药大学学报》 2026 (1)
1-5,5
1.国家自然科学基金项目(82460918)2.贵州省科技计划项目(黔科合基础-ZK[2024]一般404).
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