卷积神经网络与Vision Transformer在胶质瘤中的研究进展OA
Research progress of convolutional neural network and vision transformer in gliomas
胶质瘤因高度异质性、强侵袭性及预后差,传统诊疗面临巨大挑战.深度学习技术的引入为其精准诊疗提供了新路径,其中卷积神经网络(convolutional neural network,CNN)与Vision Transformer(ViT)是核心工具.CNN凭借层级化卷积操作在局部特征提取(如肿瘤边缘、纹理细节)上具有天然优势,而ViT基于自注意力机制在全局上下文建模(如肿瘤跨区域异质性、多模态关联)方面表现突出,二者的融合策略通过整合局部精细特征与全局关联信息,在应对胶质瘤边界模糊、跨模态数据异构性等临床难题中展现出显著优势.本文综述了二者在胶质瘤检测与分割、病理分级、分子分型、预后评估等关键临床任务中的研究进展,阐述了原理、单独应用及融合策略.同时,本文也探讨了当前研究中存在的挑战,诸如对数据标注的强依赖性、模型可解释性不足等问题,并展望了未来的发展方向,例如构建轻量化架构、发展自监督学习以及推进多组学融合等前沿,以期为胶质瘤智能诊断提供系统性参考.
Gliomas pose significant challenges to traditional diagnosis and treatment due to their high heterogeneity,strong invasiveness,and poor prognosis.The introduction of deep learning(DL)technology has opened up a new avenue for their precise diagnosis and treatment,among which convolutional neural network(CNN)and Vision Transformer(ViT)are core tools.CNN inherently excels in local feature extraction(e.g.,tumor edges,texture details)through hierarchical convolution operations,while ViT stands out in global context modeling(e.g.,cross-regional heterogeneity of tumors,multimodal correlations)based on the self-attention mechanism.The fusion strategy of CNN and ViT integrates local fine-grained features with global associated information,demonstrating remarkable advantages in addressing clinical dilemmas such as blurred glioma boundaries and cross-modal data heterogeneity.This article reviews the research progress of CNN and ViT in key clinical tasks of gliomas,including detection and segmentation,pathological grading,molecular subtyping,and prognosis assessment.It elaborates on their principles,individual applications,and fusion strategies.Furthermore,it discusses the prevailing challenges in the field,such as the heavy reliance on annotated data and insufficient model interpretability,and outlines promising future research directions,including the development of lightweight architectures,the advancement of self-supervised learning paradigms,and the promotion of multi-omics integration.This review thereby provides a systematic reference for the intelligent diagnosis of gliomas.
杨浩辉;徐涛;王伟;安良良;敖用芳;朱家宝
长治医学院,长治 046000||山西医科大学附属运城市中心医院神经外科,运城 044000山西医科大学附属运城市中心医院病理科,运城 044000山西医科大学附属运城市中心医院放疗科,运城 044000山西医科大学附属运城市中心医院超声科,运城 044000贵州省第三人民医院急诊医学科,贵阳 550001山西医科大学附属运城市中心医院神经外科,运城 044000
医药卫生
胶质瘤深度学习卷积神经网络Vision Transformer磁共振成像
gliomadeep learningconvolutional neural networkvision transformermagnetic resonance imaging
《磁共振成像》 2026 (1)
168-174,7
Scientific Research Project of Shanxi Provincial Health Commission(No.2021017). 山西省卫生健康委员会科研项目(编号:2021017)
评论