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胎儿脑发育的磁共振成像研究进展OA

Advances in magnetic resonance imaging of fetal brain development

中文摘要英文摘要

胎儿MRI是先进的产前影像诊断技术,它在传统解剖学检查范畴外,能对胎儿脑部及其他器官在子宫内的代谢和功能发育情况进行无创评估.随着MRI技术快速发展,胎儿MRI逐渐成为了解胎儿发育和早期辨别神经系统异常的有力方法.目前国内胎儿MRI研究主要对正常胎儿神经系统发育评估及畸形胎儿脑结构的研究,而对胎儿脑功能发育轨迹,预测出生结局及神经行为能力研究不足.本文主要利用多种MRI新技术对胎儿脑部静脉发育、代谢、微观结构和功能连接的磁共振研究进展进行综述,并指出今后研究方向.本综述将为评估正常胎儿脑发育模式、早期发现胎儿脑部发育异常提供新方法,通过观察脑部功能、代谢活动变化,发现异常代谢、神经信号,为疾病的早期诊断及出生后治疗提供依据.

Fetal magnetic resonance imaging(MRI)is an advanced prenatal imaging diagnostic technology.Beyond the scope of traditional anatomical examinations,it enables non-invasive assessment of in utero metabolic and functional development of the fetal brain and other organs.With the rapid advancement of magnetic resonance technology,fetal functional MRI is expected to become a powerful method for understanding fetal development and early identification of neurological abnormalities and other fetal diseases.At present,the research on fetal magnetic resonance imaging in China mainly focuses on the assessment of normal fetal nervous system development and the study of brain structure in malformed fetuses.However,there is a lack of research on the trajectory of fetal brain functional development,prediction of birth outcomes,and neurobehavioral abilities.This article mainly discusses the progress in magnetic resonance research on fetal brain venous development,metabolism,microstructure,and functional connectivity,and points out the future research directions.This review will provide new methods for evaluating the normal brain development pattern of the fetus and early detection of fetal brain development abnormalities.By observing changes in brain function and metabolic activity,abnormal metabolism and neural signals can be identified,providing a basis for early diagnosis and postnatal treatment of diseases.

杨维新;王荣品

遂宁市中心医院放射影像科,遂宁 629000贵州省人民医院放射科,贵阳 550002

医药卫生

胎儿磁共振成像扩散加权成像扩散张量成像磁敏感加权成像体素内不相干运动磁共振波谱静息态功能磁共振成像

fetalmagnetic resonance imagingdiffusion weighted imagingdiffusion tensor imagingsusceptibility weighted imagingintravoxel incoherent motionmagnetic resonance spectroscopyrest-state function magnetic resonance imaging

《磁共振成像》 2026 (1)

123-127,5

Guizhou Provincial Science and Technology Program(No.Qiankehe Support[2019]2810). 贵州省科技计划项目(编号:黔科合支撑[2019]2810号)

10.12015/issn.1674-8034.2026.01.019

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