基于mHealth对2型糖尿病患者发生疼痛性糖尿病周围神经病变的影响因素分析OA
Analysis of influencing factors of painful diabetic peripheral neuropathy in patients with type 2 diabetes based on mHealth
目的:利用mHealth技术剖析2型糖尿病进展为痛性糖尿病周围神经病变(PDPN)的危险因素.方法:按是否发生PDPN将102例2型糖尿病患者分为病变组(n=30)与未病变组(n=72),收集患者的临床资料,包括年龄、性别、糖尿病病程、体质量指数(BMI)、空腹血糖、糖化血红蛋白、甘油三酯;mHealth应用相关数据:mHealth应用使用频率、使用时长、患者对mHealth干预的满意度、mHealth干预依从性等;比较两组患者各指标的差异,分析2型糖尿病患者发生PDPN的独立危险因素;并通过绘制受试者工作特征(ROC)曲线,评估各危险因素对PDPN的预测价值.结果:两组患者在空腹血糖、糖化血红蛋白、甘油三酯、mHealth使用频率及时长等指标比较,差异均统计学意义(P<0.05).糖化血红蛋白(OR=13.441)、甘油三酯(OR=8.851)为发生PDPN的独立危险因素(P<0.05),mHealth使用频率(OR=0.430)和时长(OR=0.728)为发生PDPN的保护因素(P<0.05).ROC曲线显示,四者预测PDPN的曲线下面积(AUC)均>0.75,并且糖化血红蛋白(0.887)和mHealth使用频率(0.879)的预测价值更高.结论:控制糖化血红蛋白、甘油三酯水平,提高mHealth使用频率和时长,可降低PDPN发生风险.
Objective:Leveraging mobile health(mHealth)technology,to examine the risk factors of type Ⅱ diabetes mellitus to painful diabetic peripheral neuropathy(PDPN).Methods:Based on the presence of PDPN,the 102 type 2 diabetic patients were split into two groups:30 were lesioned and 72 were not.Age,gender,duration of diabetes,body mass index(BMI),fasting blood glucose,glycated hemoglobin,and triglycerides were among the clinical data gathered.Patient satisfaction with the mHealth intervention,adherence to the mHealth intervention,frequency of use,and duration of use were among the data pertaining to mHealth applications.The independent risk factors of PDPN in type 2 diabetes patients were analyzed by comparing the differences of various indicators between the two groups.ROC prediction curves were plotted to evaluate each risk factor's predictive value for PDPN.Results:Significant between-group disparities were observed in fasting plasma glucose,glycosylated hemoglobin,triglycerides,mHealth usage frequency and duration(P<0.05).Glycosylated hemoglobin(OR=13.441)and triglycerides(OR=8.851)were independent risk factors,while mHealth usage frequency(OR=0.430)and dura-tion(OR=0.728)were protective factors.ROC curve showed that the AUC of the four factors in predicting PDPN was all>0.75,especially glycosylated hemoglobin(0.887)and mHealth usage frequency(0.879)with prominent efficiency.Conclusion:Controlling the levels of glycosylated hemoglobin and triglycerides and increasing the frequency and duration of mHealth usage can reduce the risk of PDPN.
杨卫红;郭向飞
北京中医药大学东直门医院肾病内分泌科四区,北京 101121首都医科大学附属北京安贞医院麻醉中心疼痛科,北京 100029
医药卫生
mHealth2型糖尿病疼痛性糖尿病周围神经病变影响因素
mHealthType 2 diabetes mellitusPainful diabetic peripheral neuropathyInfluencing factors
《川北医学院学报》 2026 (1)
29-32,4
国家卫生健康委能力建设和继续教育中心项目(PMT1001-14)北京市通州区科技计划项目(KJ2022CX064)
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