首页|期刊导航|川北医学院学报|基于倾向性匹配评分法分析达芬奇机器人与传统腹腔镜下远端根治术治疗胃癌的临床价值

基于倾向性匹配评分法分析达芬奇机器人与传统腹腔镜下远端根治术治疗胃癌的临床价值OA

Clinical value of Da Vinci robot or traditional laparoscopic distal radical resection in the treatment of gastric cancer based on propensity score matching

中文摘要英文摘要

目的:基于倾向性匹配评分法分析达芬奇机器人与传统腹腔镜下远端根治术治疗胃癌的临床价值.方法:收集接受远端胃癌根治术的胃癌患者的病历资料,按照手术方式不同分为机器人组(达芬奇机器人手术,n=85)和腹腔镜组(传统腹腔镜手术,n=81).采用倾向性匹配评分法(1∶1最近邻匹配,卡钳值0.2)平衡一般资料,最终获得每组63对患者进行手术,术后随访6个月.比较两组患者围术期指标(手术时间、淋巴结清扫数目、术后首次流质饮食时间、腹腔引流量、术后首次肛门排气时间、术后下床活动时间、术后住院时间)、炎症因子[C反应蛋白(CRP)、降钙素原(PCT)、血小板与淋巴细胞比值(PLR)、中性粒细胞与淋巴细胞比值(NLR)、白细胞计数(WBC)]、肿瘤标志物[癌抗原19-9(CA19-9)、癌胚抗原(CEA)]、术后并发症发生情况及复发情况.结果:治疗后,机器人组患者淋巴结清扫数目、首次肛门排气时间、腹腔引流量、术后下床活动时间均优于腹腔镜组(P<0.05);PLR、WBC、NLR、PCT、CRP低于腹腔镜组(P<0.05).两组患者CA19-9、CEA水平、复发率、并发症发生率比较,差异无统计学意义(P>0.05).结论:达芬奇机器人手术可提升手术效率和淋巴结清扫效果,减少术后炎症反应,且不增加术后风险.

Objective:To explore the clinical application value of Da Vinci robot or traditional laparoscopic distal radical resection in the treatment of gastric cancer based on propensity score matching.Methods:The medical records of patients with gastric cancer who received distal radical resection of gastric cancer were collected.According to the different surgical methods,they were divided into robot group(Da Vinci robotic surgery,n=85)and laparoscopic group(traditional laparoscopic surgery,n=81).The propensity score matching(1∶1 nearest neighbor matching,caliper value of 0.2)was used to balance the baseline data.Finally,63 pairs of data in each group were obtained.Both groups followed up for 6 months after surgery.The perioperative indexes(surgical time,number of lymph node dissection,postoperative first liquid diet time,abdominal drainage volume,postoperative first anal exhaust time,postoperative ambulation time,postoperative hospital stay),inflammatory factors[C-reactive protein(CRP),procalcitonin(PCT),platelet-to-lymphocyte ratio(PLR),neutrophil-to-lymphocyte ratio(NLR),white blood cell count(WBC)],tumor markers[cancer antigen 19-9(CA19-9),carcinoembryonic antigen(CEA)],postoperative complications and recurrence rate were compared between the two groups.Results:After treatment,the number of lymph node dissection,postoperative first anal exhaust time,abdominal drainage volume and postoperative ambulation time in robot group were better than those in laparoscopic group(P<0.05).The levels of PLR,WBC,NLR,PCT and CRP in robot group were lower compared to laparoscopic group(P<0.05).There were no statistical differences in the levels of CA19-9 and CEA,recurrence rate and incidence rates of complications between the two groups(P>0.05).Conclusion:Da Vinci robot surgery can improve the surgical efficiency and lymph node dissection effect,and reduce the postoperative inflammatory response,and it does not increase postoperative risk.

薛钧泽;王昆;林浩;张益豪;焦学龙;谭晓杰;江海涛

青岛大学,山东 青岛 266100||青岛大学附属医院胃肠外科,山东 青岛 266000青岛大学附属医院胃肠外科,山东 青岛 266000青岛大学附属医院胃肠外科,山东 青岛 266000青岛大学附属医院胃肠外科,山东 青岛 266000青岛大学附属医院胃肠外科,山东 青岛 266000青岛大学附属医院胃肠外科,山东 青岛 266000青岛大学附属医院胃肠外科,山东 青岛 266000

医药卫生

倾向性匹配评分达芬奇机器人手术传统腹腔镜手术胃癌应用价值

Propensity score matching methodDa Vinci robot surgeryTraditional laparoscopic surgeryGastric cancerApplication value

《川北医学院学报》 2026 (1)

24-28,5

吴阶平医学基金会(320.6750.19089-47)

10.3969/j.issn.1005-3697.2026.01.005

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