中老年2型糖尿病患者25-羟维生素D水平与血脂异常发生风险的关系OA

Objective:To explore and analyze the association between 25-hydroxyvitamin D(25-OH-VitD)levels and the risk of dyslipidemia in middle-aged and elderly patients with type 2 diabetes.Method:A total of 45 middle-aged and elderly patients with type 2 diabetes were enrolled as the study group from June 2024 to May 2025,and 45 healthy middle-aged and elderly individuals were selected as the control group.All participants underwent questionnaires,physical examinations,and biochemical tests.Pearson correlation analysis was used to evaluate the correlation between 25-OH-VitD levels and glucose and lipid parameters.Multiple linear regression analysis was used to explore the predictive effect of 25-OH-VitD levels on the risk of dyslipidemia.Result:The observation group demonstrated significantly higher levels of FBG,HbA1c,TC,TG,and LDL-C,along with significantly lower levels of 25-OH-VitD and HDL-C compared to the control group(P<0.05).Pearson correlation analysis revealed significant inverse correlation between 25-OH-VitD levels and FBG,HbA1c,TC,TG,and LDL-C levels,while a significant positive correlation was observed with HDL-C levels(P<0.05).Furthermore,multiple linear regression analysis confirmed that 25-OH-VitD was independently associated with FBG,HbA1c,TC,TG,and LDL-C levels.Conclusion:Low levels of 25-OH-VitD are closely associated with poor glycemic control and increased risk of dyslipidemia in patients with type 2 diabetes.