基于"湿盛阳微"理论的痛风性关节炎病机演变与分期论治OA

Gouty arthritis is a metabolic inflammatory disease caused by urate deposition.It is clinically characterized by severe joint pain,swelling,and fever.This paper thoroughly discusses the theory of"When damp prevails,Yang declines",and systematically analyzes the etiology,pathogenesis and staged treatment of gouty arthritis based on this theory.The ar-ticle holds that the dysfunction of transportation and transformation in the middle Jiao and the endogenous dampness are the basis of the disease,the failure of Yang Qi and the resulting turbid retention are the central pathogenic links,and pro-longed disease leading to collateral involvement,as well as the congealing of phlegm and blood stasis,represents the final outcome.Based on this,the treatment principles of regulating middle Jiao,clearing dampness-heat,and unblocking meridi-ans and collaterals are proposed.The purpose of this paper is to systematically explain the pathogenesis and evolution of gouty arthritis based on the theory of"When damp prevails,Yang declines",in order to provide new theoretical support and clinical strategies for TCM syndrome differentiation and individualized treatment of gouty arthritis.