退行性颈脊髓病标准化生物样本库的建立与管理中西医专家共识(2025年版)OA

This consensus aims to provide systematic and standardized integrated traditional Chinese and Western medi-cine guidance for the establishment and management of a standardized biobank for degenerative cervical myelopathy(DCM).With the intensification of population aging,DCM has become a significant disease that severely affects the quali-ty of life of middle-aged and elderly individuals.The consensus states that establishing a high-quality,disease-specific DCM biobank,integrating clinical data,imaging data,biological samples(e.g.,blood,urine),and traditional Chinese medicine(TCM)syndrome information,is of great importance for advancing research into disease mechanisms,early diagnosis,effi-cacy evaluation,and precision treatment with TCM.The consensus content covers the entire process management of the biobank,including scientific research project initiation and ethical review,sample collection and processing(adhering to relevant domestic and international standards),data integration(encompassing clinical,imaging,functional scale,and TCM syndrome differentiation data),quality control,long-term storage,and follow-up systems.It particularly emphasizes the characteristics of integrated traditional Chinese and Western medicine by combining modern multi-omics technologies with the holistic concept of TCM to explore biomarkers for DCM and the mechanisms of TCM interventions.This consensus was jointly developed by a multidisciplinary expert team and is applicable to all research institutions and medical units involved in the collection,storage,use,and disposal of DCM biological samples and data,aiming to promote data sharing and scientific research collaboration and to enhance the overall diagnosis and treatment level of DCM.