中药防治猪流行性腹泻及增效作用机制研究进展OA

Porcine epidemic diarrhea virus(PEDV)is one of the high-risk pathogens in the pig farming industry and poses a significant threat to global pig farming.More seriously,due to the high variability of the virus and its immune escape characteristics,it poses a more severe challenge to traditional vaccines and chemical control drugs.Based on the multi-target synergistic intervention effect of traditional Chinese medicine(TCM)formulas,TCM has become one of the hot directions in the current antiviral research field.This paper comprehensively reviews the domestic and international research progress of TCM in the prevention and control of porcine epidemic diarrhea(PED),and systematically summarizes the prevention and control effects and mechanisms of action of the latest TCM formulas.At the same time,combined with modern TCM technology,involving technologies such as artificial intelligence,network pharmacology,TCM nanotechnology,and TCM probiotic fermentation,it sorts out and summarizes the multi-path and multi-strategy enhancement of TCM,and looks forward to the development direction and application prospects of TCM in the prevention and treatment of PED,providing safer and more effective TCM compound preparations for the prevention and control of PED,and also providing reference for the prevention and control of other animal viral diseases.