电刺激皮层听觉诱发电位P1-N1在无残余听力患者中的初步观察OA

Objective To provide evidence for cochlear implantation(CI)in patients with no residual hearing by observing electrically evoked cortical auditory evoked potentials(CAEP)after CI surgery.Methods Five children(six ears)with prelingual deafness and no residual hearing,as confirmed by preoperative objective and subjective hearing tests,were selected.Electrically evoked P1-N1 CAEP testing was conducted after device activation.For patients implanted for more than six months,scores from the Categories of Auditory Performance-Ⅱ(CAP-Ⅱ)and the Speech Intelligibility Rating(SIR)scale were recorded.Results Typical P1-N1 waveform responses were recorded in all five patients(six ears)at various stimulation levels,with P2 waves also observed in some children.The P1 latency ranged from 37.3 to 125.8 ms,and the N1 latency from 150.8 to 205.4 ms.The three patients implanted for more than six months achieved CAP-Ⅱ scores≥6 and SIR scores≥3,indicating favorable auditory and speech development as well as communication abilities.Conclusion This study preliminarily verifies the integrity of the auditory pathway in these patients.The majority of children with no residual hearing can undergo cochlear implantation.