首页|期刊导航|陕西中医药大学学报|揿针联合疏肝调神针法治疗卒中后抑郁疗效观察

揿针联合疏肝调神针法治疗卒中后抑郁疗效观察OA

Observation of the Efficacy of Acupuncture Combined with Liver Soothing and Mind-Regulating Acupuncture in the Treatment of Post-Stroke Depression

中文摘要英文摘要

目的 观察揿针联合疏肝调神针法治疗卒中后抑郁的临床疗效.方法 招募 60 例卒中后抑郁患者,采用随机数字表法分为对照组(30 例)和治疗组(30 例);两组患者均给予原发病药物治疗,在此基础上对照组加氟哌噻吨美利曲辛片口服,治疗组加揿针及疏肝调神针法治疗,其中揿针治疗穴取内关、神门、心俞、肝俞、脾俞、肾俞;疏肝调神针法治疗穴取百会、印堂、合谷、太冲、足三里、三阴交、中脘、气海、关元.治疗 4 w后观察两组汉密尔顿抑郁量表(HAMD-17)评分、改良Barthel指数(MBI)评分、美国国立卫生研究院卒中量表(NIHSS)评分和血清脑源性神经营养因子(BDNF)、同型半胱氨酸(HCY)水平变化,比较两组疗效.结果 治疗组患者总有效率高于对照组(P<0.05).治疗后,两组患者 HAMD-17 评分、NIHSS评分均低于治疗前(P<0.05),MBI评分高于治疗前(P<0.05);血清BDNF水平高于治疗前(P<0.05),HCY水平低于治疗前(P<0.05).结论 揿针联合疏肝调神针法对PSD患者疗效较好,可调控血清BDNF、HCY水平,改善患者的抑郁症状及神经功能缺损,提高患者的生活能力.

Objective To observe the clinical efficacy of acupuncture combined with liver soothing and regulating acupuncture in the treatment of post-stroke depression.Methods A total of 60 patients with post-stroke depressio were recruited and divided into control group(30 cases)and observation group(30 cases)by random number table method.The patients in both groups were treated with drugs for the primary disease,on this basis,the control group was given oral administration of haloperidol and melitripxin tablets,and the observation group was treated with acupuncture and liver soothing and mental acupuncture,among which acupuncture was used to treat Neiguan,Shenmen,Xinyu,Liver,Spleen and Kidney.The acupuncture method of soothing the liver and regulating the mind is used to treat acupoints from Baihui,Yintang,Hegu,Taichong,Zusanli,Sanyinjiao,Zhongguan,Qihai and Guanyuan.After 4 weeks of treatment,the changes of Hamilton Depression Rating Scale(HAMD-17)score,modified Barthel index(MBI)score,National Institutes of Health Stroke Scale(NIHSS)score,serum brain-derived neurotrophic factor(BDNF)and homocysteine(HCY)levels were observed between the two groups,and the efficacy of the two groups was compared.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the HAMD-17 score and NIHSS score in both groups were lower than those before treatment(P<0.05),and the MBI score was higher than that before treatment(P<0.05).The serum BDNF level was higher than before treatment(P<0.05),and the HCY level was lower than that before treatment(P<0.05).Conclusion Acupuncture combined with liver soothing and neurotherapy acupuncture has a good effect on patients with PSD,which can regulate the levels of serum BDNF and HCY,improve the depressive symptoms and neurological deficits of patients,and improve the living ability of patients.

雍启正;卢尹凤;樊吟秋;肖洪波;杨骏

安徽中医药大学第三附属医院,安徽 合肥 230031安徽中医药大学第三附属医院,安徽 合肥 230031安徽中医药大学第一附属医院,安徽 合肥 230031安徽中医药大学第一附属医院,安徽 合肥 230031安徽中医药大学第一附属医院,安徽 合肥 230031

医药卫生

揿针疏肝调神针法卒中后抑郁脑源性神经营养因子同型半胱氨酸

pressing needleliver soothing and regulating acupuncturepost-stroke depressionbrain-derived neurotrophic factorhomocysteine

《陕西中医药大学学报》 2026 (1)

40-44,5

国家自然科学基金项目(82104994)安徽省自然科学基金项目(109066010008)安徽省临床医学研究转化专项(皖科社秘[2023]310号)安徽省第一批省级区域中医康复中心建设项目(皖中医药服务秘[2022]34号)安徽中医药大学校级自然科学研究项目(2020sfyzc12)

10.13424/j.cnki.jsctcm.2026.01.07

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