PCT联合SII对脓毒症患者病情转归的预测价值OA

Aim To analyze the predictive value of procalcitonin(PCT)combined with the systemic immune inflammatory index(SII)for the disease outcomes of sepsis patients.Methods The clinical data of 81 sepsis patients admitted to our hospital were retrospectively analyzed.They were divided into a sepsis group(24 cases without shock)and a septic shock group(57 cases)based on whether shock occurred upon admission;According to the outcome after 28 days of treatment,they were divided into the poor outcome group(20 cases,death or loss to follow-up after abandoning treatment)and the good outcome group(61 cases,discharge or transfer to the intensive care unit).The PCT and SII levels were compared between the septic shock group and the sepsis group,as well as between the good outcome group and the poor outcome group at admission,3 days after admission,and 7 days after admission.ROC curve analysis was used to evaluate the predictive efficacy of PCT and SII for disease outcomes in sepsis patients upon admission.Results At admission,3 days after admission,and 7 days after admission,PCT and SII were higher in the septic shock group and poor outcome group than those in the sepsis group and good outcome group,respectively(P<0.05).The proportion of septic shock patients in the poor outcome group was higher than that in the good outcome group(P<0.05).The ROC curve analysis results showed that the AUC of PCT,SII,and their combined prediction of poor prognosis in sepsis patients at admission were 0.522,0.545,and 0.892,respectively.Conclusion The levels of PCT and SII in sepsis patients upon admission are related to the severity and prognosis of their conditions,and combined detection has a high predictive power for the patient's disease outcome.