首页|期刊导航|辽宁中医药大学学报|经典名方五苓散的关键信息考证及临床应用分析

经典名方五苓散的关键信息考证及临床应用分析OA

Textual Research of Key Information of Classic Prescription Wuling Powder(五苓散)Based on Ancient and Modern Literature

中文摘要英文摘要

五苓散是仲景创制苓桂剂中的代表方剂,以善治"蓄水证"而闻名,其主要治疗为太阳表邪未解内传膀胱腑而致水饮内停的太阳经腑同病的水气病,临床各科凡是津液运行失调,气不化水均可使用.历代医家对五苓散应用及讨论极多且繁杂,需梳理源流并对其方名组成、药物基原、药物炮制、煎服方法等疑点进行梳理讨论.根据诸多学者考证结果,确定五苓散药物基原为猪苓用多孔菌科真菌猪苓Polyporus umbellatus的干燥菌核,茯苓用多孔菌科真菌茯苓Poria cocos的干燥菌核,泽泻用泽泻科植物东方泽泻Alisma orientale或泽泻A.plantago-aquatica的干燥块茎,白术用菊科植物白术Atractylodes macrocephala的干燥根茎,桂枝用樟科植物肉桂Cinnamomum cassia的干燥嫩枝.按照汉代度量衡制进行剂量折算,建议五苓散煎服剂量与方法为"猪苓(去黑皮,生品)10.35 g,茯苓片(去皮)10.35 g,泽泻17.25 g,白术10.35 g,桂枝(去皮)6.90 g.将5味药材磨制成粉,需过二号筛.煎服法为取5 g药末用适量米汤煎煮,每日3次.服用后嘱咐多饮热水,直至汗出病愈."现代五苓散临床应用广泛,多用于泌尿生殖系统、消化系统、心脑血管系统、眼耳鼻喉系统等多系统疾病,使用频率较高的疾病分别为心力衰竭、肝硬化腹水、腹泻、水肿等.通过对五苓散古籍文献分析考证,并结合现行标准和临床研究,确定其关键信息,以期为经典名方的临床应用及新药研发的统一质量控制提供参考.

Wuling Powder(五苓散)is a representative prescription in Linggui prescription created by ZHANG Zhongjing,which is famous for treating stagnated fluid syndrome,and mainly used in water retention of Taiyang meridian and Fu-organs with the pathogenesis of exterior evil of Taiyang does not resolve then internally transmit to the bladder causing amassment of water.It can widely be applied in syndrome with imbalanced transmission of body fluid and Qi fails to promote water.Medical experts have abundant and miscellaneous discussions about the clinical application of Wuling Powder,and it is necessary to sort out the origin and research prescription name and composition,herb origins,drug preparation methods,decocting and taking methods and other doubtful points.According to the research results of many scholars,Zhuling(Polyporus)is the dry sclerotia of Polyporus umbellatus(Pers.)Fries,Fuling(Poria)is the dry sclerotia of Poria cocos(Schw.)Wolf.,Zexie(Alismatis Rhizoma)is the dried tubers of Alisma orientale or A.plantago-aquatica,Baizhu(Atractylodis Macrocephalae Rhizoma)is the dry tubers of Atractylodes macrocephala Koidz.,Guizhi(Cinnamomi Ramulus)is the young branch of Cinnamomum cassia Presl.Converted from Han measurement,it's recommended that Zhuling(Polyporus)(dark bark peeled)10.35 g,Fuling(Poria)slice(peeled)10.35 g,Zexie(Alismatis Rhizoma)17.25 g,Baizhu(Atractylodis Macrocephalae Rhizoma)10.35 g,Guizhi(Cinnamomi Ramulus)peeled 6.90 g.The above herbs are grounded to powder and needs to pass the second sieve.5 g of the above powder is suggested to be decocted with appropriate amount of mice soup,and taken 3 times a day.It's recommended to drink plenty of hot water after taking the prescription until completely healed with sweating.Modern application of Wuling Powder is widely used in genitourinary system,digestive system,cardiovascular and cerebrovascular system,eye,ear,nose and throat system and other multi-system diseases.The diseases with high frequency of use are heart failure,cirrhosis ascites,diarrhea,edema and so on.Through the excavation and combing of the ancient literature of Wuling Powder,the key information is determined in order to provide scientific reference for the clinical application of classical prescriptions and the development of new drugs.

曹佳蕾;梁绿圆;陈金雨;吕星航;尹婧丹;丁子超;张淑孜;魏炳琦;任献青

河南中医药大学第一附属医院儿科医院,河南郑州 450099||河南中医药大学儿科医学院,河南郑州 450046河南中医药大学第一附属医院儿科医院,河南郑州 450099||河南中医药大学儿科医学院,河南郑州 450046河南中医药大学儿科医学院,河南郑州 450046河南中医药大学儿科医学院,河南郑州 450046河南中医药大学儿科医学院,河南郑州 450046河南中医药大学第一附属医院儿科医院,河南郑州 450099||河南中医药大学儿科医学院,河南郑州 450046河南中医药大学第一附属医院儿科医院,河南郑州 450099||河南中医药大学儿科医学院,河南郑州 450046河南中医药大学中医学院,河南郑州 450046河南中医药大学第一附属医院儿科医院,河南郑州 450099||河南中医药大学儿科医学院,河南郑州 450046

医药卫生

五苓散关键信息考证源流组成

Wuling Powder(五苓散)key informationtextual researchhistoric originprescription composition

《辽宁中医药大学学报》 2026 (1)

113-122,10

中央财政转移支付地方项目-中医儿科优势病种循证能力提升项目河南省中原英才计划(育才系列)项目(豫组通[2021]44号)

10.13194/j.issn.1673-842X.2026.01.018

评论