配合饲料替代冰鲜杂鱼对高体鰤幼鱼消化道结构功能、免疫及抗氧化能力的影响OA北大核心

The effects of replacing chilled trash fish with formulated feed on the digestive tract index and digestive enzyme activities,intestinal tissue structure and bacterial diversity,serum biochemical indices,hepatic im-mune-related gene expression,and antioxidant enzymes in the juvenile greater amberjack(Seriola dumerili)were studied in a 60-day aquaculture experiment.The stomach/body weight of juveniles was significantly lower in the formulated feed group compared to the chilled trash fish group.In contrast,the intestinal/body weight,intestinal trypsin activity,and villi length were markedly greater.These results indicated that the formulated feed reduced digestive capacity in the intestines of the juveniles and also enhanced the abundance of pathogenic bacteria,leading to a decline in intestinal health.Additionally,it suppressed the serum levels of high-density lipoproteins,triglycer-ides,and total cholesterol but improved the immune function by regulating the MyD88 signaling pathway.It also enhanced the serum total antioxidant capacity but reduced the serum and liver malondialdehyde levels,thereby bol-stering the antioxidant capacity.Thus,this study demonstrated the excellent potential of developing a compound feed for juvenile greater amberjack while noting that the formulated feed should be further adjusted and optimized through further research.