牙髓干细胞在牙槽骨再生中的成骨作用及影响因素OA
Osteogenic effect and factors that influence dental pulp stem cells in alveolar bone regeneration
牙髓干细胞具有自我更新和分化为多种细胞类型的潜力,可将其移植到牙槽骨缺损区域,诱导其分化为成骨细胞,从而促进牙槽骨的再生与重建.本文综述了牙髓干细胞在牙槽骨再生中的成骨能力以及影响其成骨能力的因素,分析了牙髓干细胞应用于临床所面临的问题,旨在为牙髓干细胞修复牙槽骨的基础研究和临床应用提供思路.
Dental pulp stem cells(DPSCs)have potential for self-renewal and differentiation into various cell types.They can be transplanted into the defect area of the alveolar bone to induce their differentiation into osteoblasts,thereby promoting the regeneration and reconstruction of the alveolar bone.This study reviews the osteogenic ability of DPSCs in alveolar bone regeneration and the factors that influence their osteogenic ability.The challenges faced in the clinical appli-cation of DPSCs are analyzed to provide insights into the basic research and clinical application of DPSCs for repairing the alveolar bone.
丁成兴;李小兰;杨明理
遵义医科大学基础医学院 遵义 563000遵义医科大学口腔医学院 遵义 563000遵义医科大学基础医学院 遵义 563000
医药卫生
牙髓干细胞牙槽骨骨缺损骨再生
dental pulp stem cellalveolar bonebone defectbone regeneration
《国际口腔医学杂志》 2026 (1)
43-50,8
Project of Zunyi Science and Technology Department(Zunyi Science and Technology Cooperation Project HZ[2020]36)Project of Guizhou Province Science and Technology Department(Guizhou Science and Technology Coo-peration[2018]5772-043)2023 Science and Technology Fund Project of Guizhou Provincial Health Commission(gz-wkj2023-520) 遵义市科技计划项目(遵市科合HZ字2020-36)遵义医科大学2018年度学术新苗培养及创新探索专项项目(黔科合平台人才[2018]5772-043)2023 年度贵州省卫生健康委科学技术基金(gzwkj2023-520)
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