腹腔镜—内镜系统联合根治术治疗早期胃癌老年患者的效果评估OA

Objective To investigate the short-term and long-term curative efficacy of laparoscopic endoscopic system com-bined with radical surgery in the treatment of elderly patients with early gastric cancer and its effect on gastrin and nutritional levels.Methods A total of 100 elderly patients with early gastric cancer admitted to the First Affiliated Hospital of Xinjiang Medical Univer-sity from January 2012 to December 2022 were selected as the study subjects and randomly divided into the study group and the control group,with 50 cases in each group.The control group was given laparotomy,and the study group was given laparoscopic endoscopic system combined with radical surgery.The short-term curative efficacy,long-term curative efficacy,gastrin,nutritional level and post-operative complications were compared between the two groups.Results Compared with the control group,the study group had longer operation time,less intraoperative blood loss,and shorter postoperative first exhaust time,time to get out of bed,and hospital stay(P<0.05).There were no significant differences in the recurrence rate,mucosal survival rate,submucosal survival rate,and overall survival rate between the two groups(P>0.05).Compared with the control group,the study group had higher postoperative GAS and MTL levels and lower CCK levels(P<0.05);ALB,PAB,and HB levels(P<0.05);the control group had significant differences from the preoperative group(P<0.05).Overall complication rate was lower(P<0.05).Conclusion Laparoscopic-endoscopic sys-tem combined with radical surgery can significantly improve the short-term efficacy of elderly patients with early gastric cancer,with less effect on gastrin secretion and nutritional level of the body,and fewer postoperative complications.