重构本草之豨莶草OA
Reconstruction of Chinese materia medica:Herba Siegesbeckiae
通过古籍文献调研、中医药现代研究成果的梳理,结合中医临床及中药学等学科领域内知名专家学者的认识及应用经验,归纳出豨莶草功效主要为祛风湿,利关节,解毒;症靶为关节疼痛、中风偏瘫,标靶为风湿免疫相关指标升高.现代药理研究发现豨莶草及其有效成分具有抗炎、镇痛、调节免疫、保护脑血管及神经等作用.豨莶草有一定的毒性,故临床使用中应注意剂量与配伍,或改用酒制品.阴血不足者当慎用,孕妇不宜使用.临床常用剂量为15~30 g.
Through investigation of ancient books and the sorting of modern research achievements of traditional Chinese medicine,combined with the understanding and application experience of famous experts and scholars in desciplinary fields such as traditional Chinese medicine clinical medicine and science of Chinese materia medica,it is concluded that Herba Siegesbeckiae mainly has the effects of dispelling wind-dampness,benefiting joints,and detoxification.The symptom targets are joint pain and post-stroke hemiplegia,Biochemical indicator target is elevated levels of rheumatism and immunity-related indicators.Modern pharmacological studies have found that Herba Siegesbeckiae and its active components have anti-inflammatory,analgesic,immune regulation,and protection of cerebral blood vessels and nerves effects.Herba Siegesbeckiae has certain toxicity,so attention should be paid to dosage and compatibility in clinical use,or it can be replaced with wine-processed products.It should be used cautiously in patients with yin-blood deficiency and other syndromes.It is not suitable for pregnant women.The commonly used clinical dose is 15-30g.
谢伟楠;胡诗宛;何志远;田佳星
北京中医药大学,北京 100029中国中医科学院广安门医院,北京 100053北京中医药大学,北京 100029中国中医科学院广安门医院,北京 100053
医药卫生
豨莶草症靶标靶重构本草临床回归
Herba Siegesbeckiaesymptom targetbiochemical indicator targetreconstruction of Chinese materia medicaclinical verification
《长春中医药大学学报》 2026 (1)
32-34,3
中国中医科学院科技创新工程创新团队项目(CI2021B008)中央高水平中医医院临床研究和成果转化能力提升项目临床科研一体化人才专项(HLCMHPP20230CZ40907)中国中医科学院广安门医院临床医学研究中心建设专项经费(2022LYJSZX13)中央高水平中医医院临床研究和成果转化能力提升项目-传承名老中医药专家学术经验专项(HLCMHPP2023009)国家自然基金委-中国科学院联合项目资助中西医结合创新范式战略研究(XK2023SMC003)
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