TIPS术后肝硬化患者的营养管理:关注肌少症的影响OA
Nutrition Management of Patients with Cirrhosis Post-Transjugular Intrahepatic Portosystemic Shunt:Focus on the Impact of Sarcopenia
经颈静脉肝内门体分流术(transjugular intrahepatic portosystemic shunt,TIPS)已被证实为治疗肝硬化门静脉高压相关并发症的一种重要介入手段,但术后患者的营养管理仍面临严峻挑战.肌少症作为肝硬化营养不良的重要表现形式,严重影响患者预后.TIPS术后患者肌少症发生率高,不仅显著增加感染、肝性脑病和腹水等并发症的风险,也进一步加速失代偿进程.对TIPS术后肝硬化患者进行肌少症的系统评估与干预,有助于减少失代偿事件发生,提高生存率.因此,TIPS术后的营养管理应确立以肌少症防治为核心策略,加强对患者营养状态的早期筛查与动态评估.实施早期、积极且针对肌少症的综合性营养干预,已成为改善TIPS术后患者临床结局和长期预后的关键措施.
Transjugular intrahepatic portosystemic shunt(TIPS)has been clinically proven to be an important interventional treatment for complications related to portal hypertension in cirrhosis.However,nutritional management in post-TIPS patients remains a significant challenge.Sarcopenia,a critical manifestation of malnutrition in cirrhosis,severely impacts patient prognosis.The high incidence of sarcopenia following TIPS not only significantly increases the risk of complications such as infections,hepatic encepha-lopathy,and ascites but also further accelerates the process of decompensation.Systematic assessment and intervention for sarcopenia in cirrhotic patients after TIPS can help reduce decompensation events and improve survival rates.Therefore,nutritional management after TIPS should establish the prevention and treatment of sarcopenia as a core strategy,with enhanced early screening and dynamic evaluation of patients'nutritional status.Implementing early,proactive,and comprehensive nutritional interventions targeting sarcope-nia has become a key measure to improve clinical outcomes and long-term prognosis in post-TIPS patients.
LAI Ruimin;ZHENG Qi;CHEN Jing
Department of Hepatology,Liver Research Center,The First Affiliated Hospital,Fujian Medical University,Fuzhou 350005,China||Institute for Liver Desease,Fujian Medical University,Fuzhou 350005,China||Department of Hepatology,National Regional Medical Center,Binhai Campus of the First Affiliated Hosptial,Fujian Medical University,Fuzhou 350212,ChinaDepartment of Hepatology,Liver Research Center,The First Affiliated Hospital,Fujian Medical University,Fuzhou 350005,China||Institute for Liver Desease,Fujian Medical University,Fuzhou 350005,China||Department of Hepatology,National Regional Medical Center,Binhai Campus of the First Affiliated Hosptial,Fujian Medical University,Fuzhou 350212,ChinaDepartment of Hepatology,Liver Research Center,The First Affiliated Hospital,Fujian Medical University,Fuzhou 350005,China||Institute for Liver Desease,Fujian Medical University,Fuzhou 350005,China||Department of Hepatology,National Regional Medical Center,Binhai Campus of the First Affiliated Hosptial,Fujian Medical University,Fuzhou 350212,China
医药卫生
肝硬化经颈静脉肝内门体分流术营养管理肌少症
CirrhosisTransjugular intrahepatic portosystemic shuntNutrition managementSarcopenia
《西南医科大学学报》 2026 (1)
16-19,4
福建省科技厅社会发展引导性(重点)项目(2023Y0015)
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