肝硬化难治性腹水的诊治进展OA

Refractory ascites of cirrhosis is a common and serious complication in patients with advanced cirrhosis.Its treatment is difficult and has a poor prognosis,which poses a significant burden on the patient's quality of life and the medical system.At pres-ent,clinical treatment methods have problems with localized efficacy and obvious side effects.It is urgent to systematically summarize the existing research progress and explore better solutions.This paper compares and analyzes the clinical value of traditional treatment methods and new intervention strategies by sorting out recent literature,combining the pathological mechanism and clinical practice of refractory ascites with cirrhosis.Studies have found that although traditional methods such as sodium limiting,diuretics and repeated ascites can relieve symptoms in the short term,they can easily lead to electrolyte disorders and kidney damage,and have limited long-term effects.In the new treatment,transjugate intrahepatic portal shunt(TIPS)can significantly reduce portal venous pressure and pro-long the recurrence of ascites,but the risk of hepatic encephalopathy after surgery still needs attention;ascites concentrating and retraction technology can reduce albumin consumption and maintain circulatory stability,but the operational cost is high;liver trans-plantation,as the final means of end-stage treatment,is limited by the popularization of donor resources and technology.Future research needs to further optimize the indication selection of treatment plans,balance efficacy and risks,and explore lower-cost and more sustainable intervention models through multidisciplinary collaboration.