麻杏石甘汤联合常规西医治疗老年肺部感染临床研究OA
Clinical Study on Ephedra and Apricot Kernel and Gypsum and Licorice Decoction Combined with Conventional Western Medicine in the Treatment of Elderly Patients with Pulmonary Infection
目的:观察麻杏石甘汤联合常规西医治疗老年肺部感染的临床疗效.方法:选择2024 年1 月至2025 年1 月在南阳市第一人民医院就诊的老年肺部感染患者40 例,随机分为对照组和研究组,每组各 20 例,对照组采用常规西医治疗,研究组在常规西医治疗基础上采用麻杏石甘汤治疗.两组均治疗7d,观察两组患者的临床疗效、呼吸机使用时间、住院时间及治疗前后炎症因子水平、中医证候评分、生活质量评分等.结果:对照组有效率为65.00%,研究组有效率为95.00%,两组有效率比较,差异有统计学意义(P<0.05).研究组呼吸机使用时间、住院时间较对照组明显缩短(P<0.05).两组患者治疗后,降钙素原(procalcitonin,PCT)、C反应蛋白(C-reactive protein,CRP)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)水平明显降低,且研究组低于对照组(P<0.05);喘息、肺部啰音、气短、咳嗽评分明显降低,且研究组低于对照组(P<0.05);生活质量评分明显升高,且研究组高于对照组(P<0.05).结论:麻杏石甘汤联合常规西医治疗老年肺部感染,可改善患者症状,降低炎症因子水平,缩短呼吸机使用时间和住院时间,提高患者生活质量.
Objective:To observe the clinical efficacy of Ephedra and Apricot Kernel and Gypsum and Licorice Decoction combined with conventional Western medicine on elderly patients with pulmonary infection.Methods:A total of 40 elderly patients with pulmonary in-fection admitted to Nanyan First People's Hospital from January 2024 to January 2025 were selected and randomly divided into the con-trol group and the study group,with 20 cases in each group.The control group received conventional Western medicine treatment,while the study group received Ephedra and Apricot Kernel and Gypsum and Licorice Decoction in addition to the conventional Western medi-cine treatment.Clinical efficacy,ventilator use time,hospitalization duration,levels of inflammatory factors,TCM syndrome scores,and quality of life scores,etc.were observed in the two groups.Results:The effective rate was 65.00%in the control group and 95.00%in the study group,and the difference was statistically significant between the two groups(P<0.05).The ventilator use time and hospital-ization duration in the study group were significantly shorter than those in the control group(P<0.05).After treatment,the levels of procalcitonin(PCT),C-reactive protein(CRP),and tumor necrosis factor-α(TNF-α)were significantly decreased in both groups,and the levels in the study group were lower than those in the control group(P<0.05).The scores for wheezing,pulmonary rales,shortness of breath,and cough were significantly decreased in both groups,and the above scores in the study group were lower than those in the control group(P<0.05).The quality of life scores were significantly decreased in both groups,and the scores in the study group were lower than those in the control group(P<0.05).Conclusion:Ephedra and Apricot Kernel and Gypsum and Licorice Decoction com-bined with conventional Western medicine in the treatment of elderly patients with pulmonary infection can improve their symptoms,re-duce the levels of inflammatory factors,shorten ventilator use time and hospitalization duration,and enhance their quality of life.
YAN Yun;FAN Fengjiang;ZHAO Jing;SHI Jingxin;ZUO Yuanhang;WU Jinhai
Nanyang First People's Hospital,Nanyang,Henan,China,473000Nanyang First People's Hospital,Nanyang,Henan,China,473000Nanyang First People's Hospital,Nanyang,Henan,China,473000Nanyang First People's Hospital,Nanyang,Henan,China,473000Nanyang First People's Hospital,Nanyang,Henan,China,473000Nanyang First People's Hospital,Nanyang,Henan,China,473000
医药卫生
老年肺部感染麻杏石甘汤盐酸氨溴索注射液头孢哌酮钠舒巴坦钠《伤寒论》张仲景
elderly pulmonary infectionEphedra and Apricot Kernel and Gypsum and Licorice DecoctionAmbroxol Hydrochloride In-jectionCefoperazone and Sulbactam SodiumTreatise on Cold Damage DiseasesZhang Zhongjing
《河南中医》 2026 (1)
46-50,5
南阳市基础与前沿技术研究专项项目(23JCQY1008)
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