Therapeutic approaches to diabetic macular edema assessed using optical coherence tomography and optical coherence tomography angiographyOA
Overt and harmful diabetes mellitus(DM)has detrimental effects on individuals and,by extension,the community.Among the microvascular DM complications is diabetic retinopathy(DR).DR may cause irreversible vision deterioration in cases of poor blood glucose regulation.Changes in vascular permeability are key trigger points for diabetic macular edema(DME),a condition characterized by the accumulation of fluid in the macula.The development of vascular endothelial growth factor(VEGF)pathway inhibitors has provided a pathogenesis-based treatment approach for DME.Optical coherence tomography(OCT)provides highresolution imaging of the anatomy,including the aging of DME and its structural damage,in distinct morphologic subtypes of macular edema,thereby supporting the assessment of macular edema treatment.The availability of repeated OCT monitoring provides clinical reassurance through the treatment.OCT angiography(OCTA)provides retinal blood flow maps with high spatial resolution.The ability promotes an understanding of disease pathogenesis and facilitates the implementation of new therapeutic methods.This review compares the potential of OCT and OCTA in the diagnosis and treatment of DME,as well as their respective therapeutic applications.
Parisa Alsadat Dadkhah;Hamed Taheri;Masoud Noroozi;Asma Rasouli;Zahra Sheikh;Saba Imanparvar;Saeed Zivari Lashkajani;Nahid Samadi;Javad Nadem;Behzadmehr Amirian;Goharsharieh Alishiri;Ata Akhtari Kohnehshahri;Arshia Shafiei;Amirreza Heydarlou;Reza Khademi;Anahita Rahmati;Niloofar Deravi
Student Research Committee,School of Medicine,Isfahan University of Medical Sciences,Isfahan 8174673461,IranDepartment of Dentistry and Implantology,Institute of Fundamental Medicine and Biology,Kazan(Volga Region)Federal University,Kazan 420008,RussiaDepartment of Biomedical Engineering,Faculty of Engineering,University of Isfahan,Isfahan 817467344,IranSchool of Medicine,Zanjan University of Medical Sciences,Zanjan 45139-55846,IranBoston University Chobanian&Avedisian School of Medicine,Boston Medical Center,Boston,MA 02118-2908,USAStudents Research Committee,School of Medicine,Ardabil University of Medical Sciences,Ardabil 85991-56189,IranStudent Research Committee,Kashan University of Medical Sciences,Kashan 87159-73474,IranStudent Research Committee,Babol University of Medical Sciences,Babol 47745-47176,IranSchool of Medicine,Guilan University of Medical Science,Rasht 13656-44165,IranStudent Research Committee,School of Medicine,Shahid Beheshti University of Medical Sciences,Tehran 1985717413,IranStudents Research Committee,School of Medicine,Ardabil University of Medical Sciences,Ardabil 85991-56189,IranFaculty of Medicine,Tabriz University of Medical Sciences,Tabriz 5165665931,IranStudent Research Committee,School of Medicine,Shahid Beheshti University of Medical Sciences,Tehran 1985717413,IranFaculty of Medicine,Tabriz University of Medical Sciences,Tabriz 5165665931,IranStudent Research Committee,Faculty of Medicine,Mashhad University of Medical Sciences,Mashhad 91766-97145,IranStudent Research Committee,School of Medicine,Shahid Beheshti University of Medical Sciences,Tehran 1985717413,IranStudent Research Committee,School of Medicine,Shahid Beheshti University of Medical Sciences,Tehran 1985717413,Iran
医药卫生
diabetic macular edemaoptical coherence tomographyoptical coherence tomography angiographyvascular endothelial growth factor
《International Journal of Ophthalmology(English edition)》 2026 (1)
P.160-174,15
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