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Tocilizumab as an effective treatment option for idiopathic orbital inflammation:a case report and literature reviewOA

中文摘要

Dear Editor,Idiopathic orbital inflammation(IOI),also known as orbital inflammatory pseudotumor,is a relatively common orbital disorder[1].Its pathogenesis remains unclear,often regarded as a nonspecific immune-mediated response[2].IOI presents with symptoms such as pain,photophobia,proptosis,eyelid swelling,edema,conjunctival congestion,and diplopia,with possible vision loss occurring in some cases.Based on the soft tissue structures involved,IOI can be classified into subtypes such as myositis,optic neuritis,dacryoadenitis,diffuse orbital inflammation,and orbital inflammatory masses[2].

Hai-Yang Zhang;Hui-Jie Zhang;Hui-Fang Zhou

State Key Laboratory of Eye Health,Department of Ophthalmology,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200011,ChinaState Key Laboratory of Eye Health,Department of Ophthalmology,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200011,ChinaState Key Laboratory of Eye Health,Department of Ophthalmology,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200011,China

医药卫生

soft tissue structuresidiopathic orbital inflammationorbital disorder itsvision lossmyositisoptic neuritiorbital inflammatory pseudotumorisorbital inflammation ioi alsoorbital inflammatory pseudotumor

《International Journal of Ophthalmology(English edition)》 2026 (1)

P.199-201,3

Supported by the National Natural Science Foundation of China(No.82388101,No.81930024)the Science and Technology Commission of Shanghai(No.22YS1400400,No.20DZ2270800).

10.18240/ijo.2026.01.26

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