富血小板纤维蛋白联合自体脂肪颗粒移植修复面部凹陷疗效观察OA

Objective To observe the cosmetic results of injectable platelet-rich fibrin(i-PRF)combined with autologous fat particles in repairing facial depression.Methods The clinical data of 90 patients with facial depression admitted to the hospital from December 2019 to January 2024 were retrospectively analyzed.According to different surgical methods,they were divided into control group(n=42)and combined group(n=44).The control group was repaired with autologous fat granule transplantation,and the combined group was repaired with i-PRF combined with autologous fat granule transplantation.The repair effect,survival rate of transplanted fat,secondary filling rate,complications and patient satisfaction were compared between the two groups.Results At 6 months after operation,the excellent and good repair rate of the combined group was 88.64%,which was higher than 66.67%of the control group(P＜0.05).The survival rate of transplanted fat in the combined group was higher than that in the control group at 1,3,and 6 months after operation(P＜0.05).The secondary filling rate of the combined group was lower than that of the control group(P＜0.05).There was no significant difference in the total incidence of complications between the two groups(P＞0.05).The satisfaction of patients in the combined group was higher than that in the control group(P＜0.05).Conclusion i-PRF combined with autologous fat granule transplantation in repairing facial depression can effectively improve the survival rate of transplanted fat,reduce the secondary filling rate,and has good aesthetic effect and high satisfaction of patients,which is worthy of clinical recommendation.