急性疼痛对个人与替代奖赏加工的调控效应:来自ERP的证据OA

Pain and reward are two fundamental forces that motivate behavior and regulate perceptions in humans.The interactions between these forces drive motivational decision-making.This study employed a modified Monetary Incentive Delay(MID)task combined with Event-Related Potential(ERP)techniques to examine the dynamics of reward processing under acute pain,with particular focus on the stage-specific modulation of self-oriented(personal)and other-oriented(substitute)rewards in healthy individuals. The results indicate that acute pain can significantly enhance reward-based motivation during the anticipation phase,as reflected by faster reaction times and increased button presses,with a linear increase corresponding to the magnitude of the potential reward.ERP findings reveal that,in the anticipation phase,participants in the pain group exhibited larger cue-P2 and cue-P3 amplitudes;this suggests heightened emotional processing of reward cues and increased attentional allocation to substitute rewards.Greater FRN and P3 amplitudes were observed in the pain group under substitute reward conditions in the outcome phase,indicating enhanced neural responses to socially directed reward feedback. Together,these results demonstrate a stage-dependent influence of acute pain on reward processing:while motivational responses uniformly increased across reward types,emotional and neural responses were more prominently modulated for substitute rewards.These findings provide novel evidence of the complex interplay between pain and reward systems and suggest a duality in pain-related modulation—motivational convergence and experiential dissociation—within the reward processing framework.