首页|期刊导航|影像科学与光化学|冠心病患者糖耐量与冠状动脉CTA狭窄程度和影像特点的关系

冠心病患者糖耐量与冠状动脉CTA狭窄程度和影像特点的关系OA

Relationship between Glucose Tolerance and the Stenosis Degree and Imaging Characteristics of Coronary CTA in Patients with Coronary Heart Disease

中文摘要英文摘要

目的:探究冠心病患者糖耐量与冠状动脉CT血管造影(CTA)狭窄程度和影像特点的关系.方法:回顾性分析2021年1月至2024年1月期间我院收治的294例冠心病患者的临床资料,所有患者均行冠状动脉CTA检查,并根据检查结果进行冠状动脉狭窄程度的评估.同时,对所有患者进行口服葡萄糖耐量试验(OGTT),根据血糖水平将患者分为正常糖耐量组(NGT)、糖耐量受损组(IGT)和糖尿病组(DM).比较不同糖耐量状态下,冠心病患者的冠状动脉狭窄程度和影像特点的差异,并采用Spearman分析冠心病患者糖耐量与冠状动脉CTA狭窄程度及影像特点相关性.结果:DM组患者的冠状动脉狭窄程度重度患者高于NGT组、IGT组,斑块以钙化硬斑块为主(P<0.05);IGT组冠状动脉狭窄程度中重度患者多于NGT组,斑块以混合斑块为主(P<0.05);与NGT组相比,IGT组和DM组患者的冠状动脉斑块类型存在显著差异(P<0.05);Spear-man相关分析结果显示,冠心病患者糖耐量与冠状动脉CTA狭窄程度和斑块性质呈正相关(P<0.05).结论:冠心病患者糖耐量与冠状动脉CTA狭窄程度和斑块性质之间存在显著的正相关,DM和IGT患者的冠状动脉狭窄程度和斑块性质更为严重和复杂.

Objective:To explore the relationship between glucose tolerance and stenosis degree and imaging characteristics of coronary CT angiography(CTA)in patients with coronary heart disease(CHD).Methods:The clinical data of 294 patients with CHD in the hospital between January 2021 and January 2024 were retrospectively analyzed.The severity of coronary stenosis was evaluated by results of coronary CTA.According to blood glucose levels in the oral glucose tolerance test(OGTT),patients were divided into normal glucose tolerance(NGT)group,impaired glucose tolerance(IGT)group and diabetes mellitus(DM)group.The severity of coronary stenosis and imaging characteristics in CHD patients with different glucose tolerance state were compared.The correlation between glucose tolerance and the stenosis degree,imaging characteristics of coronary CTA was analyzed by Spearman.Results:The proportion of severe coronary stenosis in DM group was higher than that in NGT group and IGT group,and plaques were mainly calcified plaques(P<0.05).The proportion of moderate to severe coronary stenosis in IGT group was higher than that in NGT group,and plaques were mainly on mixed plaques(P<0.05).Compared with NGT group,there were significant differences in types of coronary plaques in IGT group and DM group(P<0.05).The results of Spearman correlation analysis showed that glucose tolerance was positively correlated with the stenosis degree of coronary CTA and plaque properties in CHD patients(P<0.05).Conclusion:Glucose tolerance is significantly positively correlated with the stenosis degree of coronary CTA and plaque properties in CHD patients.The severity of coronary stenosis is more serious and plaque properties are more complex in DM group and IGT patients.

吾热丽卡·艾力;布阿依夏木·麦提也木;马海鸿

新疆维吾尔自治区喀什地区第二人民医院 放射影像中心,新疆 844000新疆维吾尔自治区喀什地区第二人民医院 放射影像中心,新疆 844000新疆维吾尔自治区喀什地区第二人民医院 放射影像中心,新疆 844000

医药卫生

冠心病糖耐量冠状动脉CT血管造影狭窄程度影像特点

coronary heart diseaseglucose tolerancecoronary CT angiographystenosis degreeimaging characteristic

《影像科学与光化学》 2026 (1)

33-38,6

喀什地区应用技术研究与开发计划项目(KS2021075).

10.7517/issn.1674-0475.2026.01.05

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