肺超声十四分区评分法在新生儿呼吸窘迫综合征病情评估中的应用价值OA
Application Value of Pulmonary Ultrasound 14-zone Scoring Method in Neonatal Respiratory Distress Syndrome Assessment
目的:探讨肺超声十四分区评分法在评估新生儿呼吸窘迫综合征(NRDS)病情严重程度及监测肺泡表面活性物质(PS)治疗效果中的应用价值.方法:选取2022年9月至2024年3月在我院就诊的92例NRDS患儿为研究对象,根据氧合指数(OI)分为非重症组(38例)和重症组(54例).采用日本Canon Aplio300超声诊断仪,以12 MHz高频探头进行肺超声检查,并采用十四分区评分法对两组患儿的肺部超声图像进行评分.同时,收集并分析患儿的临床血气分析指标.通过比较两组患儿肺超声征象检出率、肺超声评分以及PS治疗前后的评分变化,评估肺超声十四分区评分法的诊断效能和动态检测价值.结果:非重症组和重症组在胸膜线异常与A线消失、磨玻璃征、密集融合B线、双肺点等超声征象检出率无显著差异(P>0.05).然而,重症组在肺实变伴支气管充气征、胸腔积液的检出率上显著高于非重症组(P<0.05).肺超声十四分区评分法预测重症NRDS的最佳截断值为 35.5 分,其特异度为 92.10%,敏感度为 75.90%.此外,患儿的肺超声评分(LUS)与动脉二氧化碳分压(PaCO2)呈正相关(r=0.65,P<0.05),与动脉氧分压(PaO2)和氧合指数(OI)呈负相关(r=-0.73,P<0.05;r=-0.83,P<0.05).在PS治疗后,两组患儿的LUS均逐渐降低,且非重症组的LUS始终低于重症组(P<0.05).结论:肺超声十四分区评分法能够准确评估NRDS患儿的病情严重程度,并有效监测PS治疗后的病情变化.该方法为临床诊疗提供了有力的影像学依据,值得进一步推广和应用.
Objective:To investigate the application value of fourteen-zone pulmonary ultrasound scoring in assessing the severity of neonatal respiratory distress syndrome(NRDS)and monitoring the efficacy of pulmonary surfactant(PS)therapy.Methods:A total of 92 NRDS infants admitted to our hospital from September 2022 to March 2024 were enrolled and divided into non-critical(38 cases)and critical(54 cases)groups based on the oxygenation index(OI).Pulmonary ultrasound examinations were performed using a Canon Aplio300 ultrasound diagnostic instrument with a 12 MHz high-frequency probe.The lung ultrasound images of the two groups were scored using the fourteen-zone scoring method.Clinical blood gas analysis indices were also collected and analyzed.By comparing the detection rates of ultrasound signs,lung ultrasound scores(LUS),and score changes before and after PS treatment between the two groups,the diagnostic efficacy and dynamic monitoring value of the fourteen-zone pulmonary ultrasound scoring method were assessed.Results:There were no significant differences in the detection rates of pleural line abnormalities,A-line disappearance,ground-glass opacities,and confluent B-lines between the non-critical and critical groups(P>0.05).However,the detection rates of consolidation with air bronchogram and pleural effusion were significantly higher in the critical group than in the non-critical group(P<0.05).The optimal cut-off value of the fourteen-zone scoring method for predicting severe NRDS was 35.5 points,with a specificity of 92.10%and a sensitivity of 75.90%.Additionally,LUS was positively correlated with arterial partial pressure of carbon dioxide(PaCO2)(r=0.65,P<0.05)and negatively correlated with arterial partial pressure of oxygen(PaO2)and oxygenation index(OI)(r=-0.73,P<0.05;r=-0.83,P<0.05,respectively).After PS treatment,LUS gradually decreased in both groups,and LUS in the non-critical group was always lower than that in the critical group(P<0.05).Conclusion:The fourteen-zone pulmonary ultrasound scoring method can accurately assess the severity of NRDS and effectively monitor changes in condition after PS treatment.This method provides a powerful imaging basis for clinical diagnosis and treatment and deserves further promotion and application.
马寅闰;葛晖;程将
蚌埠医科大学附属蚌埠第三人民医院 超声科,安徽 233099蚌埠医科大学附属蚌埠第三人民医院 超声科,安徽 233099蚌埠医科大学附属蚌埠第三人民医院 超声科,安徽 233099
医药卫生
肺超声评分新生儿呼吸窘迫综合征肺泡表面活性物质
pulmonary ultrasound scoreneonatal respiratory distress syndromepulmonary surfactant
《影像科学与光化学》 2026 (1)
132-137,6
安徽省教育厅科研项目(2022AH051488)蚌埠市科技创新指导类项目(20220118).
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