血浆基质在种植体周角化黏膜增宽中的临床应用OA
The use of plasmatrix in peri-implant keratinized mucosa augmentation
充足的种植体周角化黏膜宽度对减少菌斑附着、降低种植体周黏膜炎发生率、维持种植体长期健康具有重要意义.目前虽有多种材料可用于增宽种植体周角化黏膜,但自体移植物存在手术创伤大的问题,人工替代材料则面临价格高昂的局限.血浆基质是经自体血液离心制备的产物,富含大量生长因子及天然支架结构,具有生物相容性优异、取材创伤小、来源充足及应用成本低的优势.将血浆基质应用于种植体周角化黏膜增宽,有望解决现有材料的问题.本文基于现有证据,系统介绍血浆基质的制备流程,并分享其在种植体周角化黏膜增宽中的临床应用经验,以期为临床医生提供实践参考.
An adequate width of peri-implant keratinized mucosa is crucial for reducing plaque accumulation,decreasing the incidence of peri-implant mucositis,and maintaining long-term implant health.Although various materials are currently available to widen the peri-implant keratinized mucosa,autografts are associated with considerable surgical trauma,whereas artificial substitutes are often limited by high costs.Plasmatrix,a centrifuged autologous blood product rich in growth factors and scaffold-like structures,offers advantages such as excellent biocompatibility,minimal donor-site morbidity,abundant availability,and low cost.Its application for peri-implant keratinized mucosa augmentation may help overcome the limitations of existing materials.Based on current evidence,this article presents the preparation protocol for plasmatrix and clinical experiences with its use in peri-implant keratinized mucosa augmentation,thereby providing practical guidance for clinicians.
Qiu Yun;Li Yongjun;Zhang Xiaoxin;Wang Yulan;Zeng Hao
State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,Key Laboratory of Oral Biomedicine,Ministry of Education,Hubei Key Laboratory of Stomatology,School&Hospital of Stomatology,Wuhan University,Wuhan 430079,Hubei,China||Center for Prosthodontics and Implant Dentistry,Optics Valley Branch,School and Hospital of Stomatology,Wuhan University,Wuhan 430223,Hubei,ChinaWuhan Dazhong Dental Hospital,Wuhan 430070,Hubei,ChinaState Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,Key Laboratory of Oral Biomedicine,Ministry of Education,Hubei Key Laboratory of Stomatology,School&Hospital of Stomatology,Wuhan University,Wuhan 430079,Hubei,China||Department of Implantology,Hospital of Stomatology,Wuhan University,Wuhan 430079,Hubei,ChinaState Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,Key Laboratory of Oral Biomedicine,Ministry of Education,Hubei Key Laboratory of Stomatology,School&Hospital of Stomatology,Wuhan University,Wuhan 430079,Hubei,China||Department of Implantology,Hospital of Stomatology,Wuhan University,Wuhan 430079,Hubei,ChinaState Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,Key Laboratory of Oral Biomedicine,Ministry of Education,Hubei Key Laboratory of Stomatology,School&Hospital of Stomatology,Wuhan University,Wuhan 430079,Hubei,China||Department of Implantology,Hospital of Stomatology,Wuhan University,Wuhan 430079,Hubei,China
血浆基质种植体周角化黏膜角化黏膜增宽
PlasmatrixPeri-implant keratinized mucosaKeratinized mucosa width augmentation
《中国口腔种植学杂志》 2025 (6)
536-540,5
国家自然科学基金(82401192) National Natural Science Foundation of China(82401192)
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