A Comprehensive Brain MRI and Neurodevelopmental Dataset in Children with Tetralogy of FallotOA
Background:The life-course management of children with tetralogy of Fallot(TOF)has focused on demonstrating brain structural alterations,developmental trajectories,and cognition-related changes that unfold over time.Methods:We introduce an magnetic resonance imaging(MRI)dataset comprising TOF children who underwent brain MRI scanning and cross-sectional neurocognitive follow-up.The dataset includes brain three-dimensional T1-weighted imaging(3D-T1WI),three-dimensional T2-weighted imaging(3D-T2WI),and neurodevelopmental evaluations using the Wechsler Preschool and Primary Scale of Intelligence–Fourth Edition(WPPSI-IV).Results:Thirty-one children with TOF(age range:4–33 months;18 males)were recruited and completed corrective surgery at the Children’s Hospital of Nanjing Medical University,Nanjing,China.Aiming to promote the neurodevelopmental outcomes in children with TOF,we have meticulously curated a comprehensive dataset designed to dissect the complex interplay among risk factors,neuroimaging findings,and adverse neurodevelopmental outcomes.Conclusion:This article aims to introduce our open-source dataset on neurodevelopment in children with TOF,which covers the data types,data acquisition and processing methods,the procedure for accessing the data,and related publications.
Yang Xu;Yaqi Zhang;Meijiao Zhu;Pengcheng Xue;Siyu Ma;Di Yu;Liang Hu;Yuxi Zhang;Wei Peng;Jirong Qi;Xuyun Wen;Ming Yang;Xuming Mo
Department of Cardiothoracic Surgery,Children’s Hospital of Nanjing Medical University,Nanjing,210008,ChinaNanjing Children’s Hospital,Clinical Teaching Hospital of Medical School,Nanjing University,Nanjing,210008,ChinaDepartment of Radiology,Children’s Hospital of Nanjing Medical University,Nanjing,210008,ChinaCollege of Artificial Intelligence,Nanjing University of Aeronautics and Astronautics,Jiangning District,Nanjing,211106,ChinaDepartment of Cardiothoracic Surgery,Children’s Hospital of Nanjing Medical University,Nanjing,210008,ChinaDepartment of Cardiothoracic Surgery,Children’s Hospital of Nanjing Medical University,Nanjing,210008,ChinaDepartment of Cardiothoracic Surgery,Children’s Hospital of Nanjing Medical University,Nanjing,210008,ChinaDepartment of Cardiothoracic Surgery,Children’s Hospital of Nanjing Medical University,Nanjing,210008,ChinaDepartment of Cardiothoracic Surgery,Children’s Hospital of Nanjing Medical University,Nanjing,210008,ChinaDepartment of Cardiothoracic Surgery,Children’s Hospital of Nanjing Medical University,Nanjing,210008,ChinaCollege of Artificial Intelligence,Nanjing University of Aeronautics and Astronautics,Jiangning District,Nanjing,211106,ChinaDepartment of Radiology,Children’s Hospital of Nanjing Medical University,Nanjing,210008,ChinaDepartment of Cardiothoracic Surgery,Children’s Hospital of Nanjing Medical University,Nanjing,210008,China Nanjing Children’s Hospital,Clinical Teaching Hospital of Medical School,Nanjing University,Nanjing,210008,China State Key Laboratory of Reproductive Medicine and Offspring Health,Nanjing Medical University,Nanjing,210008,China
医药卫生
Tetralogy of Fallotneurodevelopmentdatasetcongenital heart disease
《Congenital Heart Disease》 2025 (5)
P.559-570,12
supported by the National Natural Science Foundation of China(82270310)Noncommunicable Chronic Diseases-National Science and Technology Major Project(No.2024ZD0527000 and No.2024ZD0527005)Jiangsu Provincial key research and development program(BE2023662)General project of Nanjing Health Commission(YKK22166).
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