Zhizi-Bopi decoction ameliorates ANIT-induced cholestatic liver injury in mice through IL-17/NF-κB inflammatory pathwaysOA
Zhizi-Bopi decoction ameliorates ANIT-induced cholestatic liver injury in mice through IL-17/NF-κB inflammatory pathways
Wei Cui;Ya-Ping Xiao;Tian Chen;Jie-Yao Huang;Xiao-Fei Bi;Wen-Jin Zhang;Yan-Jun Hu;Li-Juan Deng;Wei Fang;Chang-Hui Liu
Department of Pharmacy,Chongqing University Three Gorges Hospital,Chongqing 404000,China||School of Medicine,Chongqing University,Chongqing 400030,ChinaDepartment of Pharmacy,Chongqing University Three Gorges Hospital,Chongqing 404000,China||School of Medicine,Chongqing University,Chongqing 400030,ChinaSchool of Medicine,Chongqing University,Chongqing 400030,China||Health Management Center,Chongqing University Three Gorges Hospital,Chongqing 404000,ChinaDepartment of Pharmacy,Chongqing University Three Gorges Hospital,Chongqing 404000,China||School of Medicine,Chongqing University,Chongqing 400030,ChinaSchool of Medicine,Chongqing University,Chongqing 400030,China||Chongqing Municipality Clinical Research Center for Endocrinology and Metabolic Diseases,Chongqing University Three Gorges Hospital,Chongqing 404000,ChinaSchool of Medicine,Chongqing University,Chongqing 400030,China||Chongqing Municipality Clinical Research Center for Endocrinology and Metabolic Diseases,Chongqing University Three Gorges Hospital,Chongqing 404000,ChinaDepartment of Pharmacy,Chongqing University Three Gorges Hospital,Chongqing 404000,China||School of Medicine,Chongqing University,Chongqing 400030,ChinaDepartment of Pharmacy,Chongqing University Three Gorges Hospital,Chongqing 404000,China||School of Medicine,Chongqing University,Chongqing 400030,ChinaDepartment of Pharmacy,Chongqing University Three Gorges Hospital,Chongqing 404000,China||School of Medicine,Chongqing University,Chongqing 400030,ChinaState Key Laboratory of Traditional Chinese Medicine Syndrome,School of Pharmaceutical Sciences,Guangzhou University of Chinese Medicine,Guangzhou 510405,China
Zhizi-Bopi decoctioncholestatic liver injurynetwork pharmacologysingle-cell RNA sequencingIL-17/NF-κB signaling pathway
Zhizi-Bopi decoctioncholestatic liver injurynetwork pharmacologysingle-cell RNA sequencingIL-17/NF-κB signaling pathway
《传统医学研究（英文版）》 2026 (1)
47-59,13
This work was supported by the National Science Foundation of China(No.82405004,82474253),the Natural Science Foundation postdoctoral project of Chongqing(CSTB2022NSCQ-BHX0709),Chongqing Wanzhou District doctoral"through train"scientific research project(wzstc-20220124),Natural Science Foundation of Chongqing,China(No.Cstc2021jcyj-msxmX0996),and Chongqing Wanzhou District Science and Health Joint Medical Research Project(wzstc-kw2023032).The sponsor had no role in the design or conduct of this research.The authors would like to express their sincere gratitude to Dr.Yunfeng Wang at Paris-Saclay University for his valuable guidance in scRNA-seq data analysis.
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