高BMI人群CCTA中P3T个性化对比剂方案与标准方案的图像质量及对比剂用量对比研究OA

Objective To investigate the clinical application value of personalized patient protocol technology(P3T)in coronary CT angiography(CCTA)for populations with high body mass index(BMI)(28-32 kg/m2).Methods A total of 65 patients scheduled for CCTA scanning in Capital Medical University Affiliated Beijing Friendship Hospital from June to December 2023 were prospectively enrolled,and randomly divided into a control group(n=33)and a P3T group(n=32).The control group selected the corresponding contrast agent injection flow rate according to different BMI values.The P3T group generated personalized injection protocols based on patients'body weight through the P3T software.The two groups were compared in terms of contrast agent dosage,injection flow rate,effective dose(ED),results of subjective evaluation of image quality,and objective evaluation of image quality[including CT values of the aortic root and each segment of the coronary artery,signal to noise ratio(SNR),and contrast to noise ratio(CNR)].Results The contrast agent dosage and injection flow rate in the P3T group were significantly lower than those in the control group(P<0.05).There were no statistically significant differences between the two groups in CT values of the aortic root and each segment of the coronary artery,SNR,CNR,and ED(P>0.05).The subjective scores of images in both groups were≥3 points,which could meet diagnostic needs,with good consistency(Kappa=0.81).Conclusion The application of P3T technology in high BMI populations can reduce contrast agent dosage and injection flow rate while ensuring image quality,realize the personalization of injection protocols and consistency of examinations,and is clinically feasible.