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基于多维特征的颅内动脉瘤风险预测与模型评估OA

Risk prediction and model evaluation of intracranial aneurysms based on multidimensional features

中文摘要英文摘要

目的 建立准确预测颅内动脉瘤(IA)的破裂风险的模型,以便于患者的早期诊断和个性化治疗.方法 结合动脉瘤的形态学特征(如最大直径、瘤颈宽度、分叶性、体积等)与血流动力学特征(如壁面剪切应力、振荡剪切指数、压力分布等),通过使用Mimics和Ansys-Fluent软件提取特征数据.基于PyTorch框架,开发了一个风险预测模型,该模型同时采用传统机器学习算法和深度学习模型进行IA破裂风险预测.结果 对于小规模数据,使用并行树提升算法和随机森林构建的机器学习模型在预测中表现较为出色,更适合IA的风险预测.结论 本研究开发的IA破裂风险预测模型能够辅助医生制定更精确的诊疗方案,从而提高治疗效果和患者安全.

Objective To accurately predict the risk of intracranial aneurysm rupture,facilitating early diagnosis and personalized treatment for patients.Methods By integrating morphological features(e.g.,maximum diameter,neck width,lobulation,volume)and hemodynamic characteristics(e.g.,wall shear stress,oscillatory shear index,pressure distribution)of aneurysms,feature data were extracted using Mimics and Ansys-Fluent software.A risk prediction model was developed based on the PyTorch framework,incorporating both traditional machine learning algorithms and deep learning models for intracranial aneurysm rupture risk prediction.Results The study demonstrated that machine learning models constructed using parallel tree boosting algorithms and random forests outperformed deep learning methods(represented by multilayer perceptrons)in predicting rupture risks,proving more suitable for intracranial aneurysm risk assessment.Conclusion The proposed aneurysm rupture risk prediction model can assist physicians in formulating more precise diagnostic and therapeutic plans,thereby improving treatment efficacy and patient safety.

李永生;陈广新;董祥梅;徐缘缘;张思瑾;吕春会

牡丹江医科大学医学影像学院,黑龙江 牡丹江 157011牡丹江医科大学医学影像学院,黑龙江 牡丹江 157011牡丹江医科大学医学影像学院,黑龙江 牡丹江 157011牡丹江医科大学医学影像学院,黑龙江 牡丹江 157011牡丹江医科大学医学影像学院,黑龙江 牡丹江 157011牡丹江医科大学医学影像学院,黑龙江 牡丹江 157011

医药卫生

机器学习医学图像处理医学图像分割深度学习模型

Machine learningMedical image processingMedical image segmentationDeep learning model

《中国医药科学》 2025 (19)

20-23,4

黑龙江省卫生健康委员会科研项目(20230909010383)黑龙江省省属高等学校基本科研业务费科研项目(2023-KYYWF-0943).

10.20116/j.issn2095-0616.2025.19.04

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