首页|期刊导航|中国医药科学|伴随继发性甲状旁腺功能亢进症的维持性血液透析患者在治疗过程中的经济毒性的研究进展

伴随继发性甲状旁腺功能亢进症的维持性血液透析患者在治疗过程中的经济毒性的研究进展OA

Research progress on financial toxicity in the treatment of maintenance haemodialysis patients with secondary hyperparathyroidism

中文摘要英文摘要

维持性血液透析患者继发性甲状旁腺功能亢进症(SHPT)作为慢性肾病最常见的并发症之一,其治疗过程中的经济毒性问题尤为突出.研究表明,SHPT患者除需要承担基础透析费用外,还需额外支付钙剂、维生素D类似物、钙敏感受体激动剂等药物费用以及相关检查费用.这些费用大部分未能纳入医保报销范围,给患者及其家庭带来了沉重的经济负担.近年研究发现,SHPT患者的经济毒性与其治疗依从性、疾病控制效果和生活质量呈显著相关性.经济负担过重可能导致患者擅自减药或停药,进而加重病情,形成恶性循环.因此,本文通过系统性回顾伴随SHPT的维持性血液透析患者的经济毒性问题,为患者降低经济毒性,优化降低经济负担的措施提供一定的指导意义.

Secondary hyperparathyroidism(SHPT)in maintenance hemodialysis patients,as one of the most common complications of chronic kidney disease,presents a particularly prominent issue of financial toxicity during its treatment.Studies indicate that SHPT patients not only bear the cost of basic dialysis but also incur additional expenses for medications such as calcium supplements,vitamin D analogs,calcimimetics,and related diagnostic tests.Most of these costs are not covered by medical insurance,imposing a heavy economic burden on patients and their families.Recent research has revealed a significant correlation between financial toxicity and treatment adherence,disease control outcomes,and quality of life in SHPT patients.Excessive financial burdens may lead patients to reduce or discontinue medications without medical guidance,exacerbating their condition and creating a vicious cycle.Therefore,this article systematically reviews the financial toxicity issues in maintenance hemodialysis patients with SHPT,aiming to provide guidance for alleviating economic burdens and optimizing cost-reduction strategies.

李柏锋;王昱晨;包若晨;张桓海;王江涛;张湘生;程凯

滨州医学院烟台附属医院甲状腺乳腺外科,山东 烟台 264100滨州医学院烟台附属医院甲状腺乳腺外科,山东 烟台 264100滨州医学院烟台附属医院甲状腺乳腺外科,山东 烟台 264100滨州医学院烟台附属医院甲状腺乳腺外科,山东 烟台 264100滨州医学院烟台附属医院甲状腺乳腺外科,山东 烟台 264100滨州医学院烟台附属医院甲状腺乳腺外科,山东 烟台 264100滨州医学院烟台附属医院甲状腺乳腺外科,山东 烟台 264100

医药卫生

经济毒性维持性血液透析继发性甲状旁腺功能亢进症治疗依从性生活质量

Financial toxicityMaintenance haemodialysisSecondary hyperparathyroidismTreatment complianceQuality of life

《中国医药科学》 2025 (18)

23-28,6

山东省医药卫生科技发展计划项目(202104010967).

10.20116/j.issn2095-0616.2025.18.04

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