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能谱CT多参数成像在阴性胆囊结石诊断中的应用价值OA

Value of Spectral CT Multiparametric Imaging in the Diagnosis of Negative Gallbladder Stones

中文摘要英文摘要

目的 探讨能谱CT的单能量成像、能谱曲线和原子序数在阴性胆囊结石诊断中的价值.方法 回顾性收集76例疑似阴性胆囊结石患者的影像学资料,且所有患者均行胆囊切除术,以手术结果为参考标准.对比阴性胆囊结石与胆汁的单能级40 keV图像、能谱曲线斜率和有效原子序数的区别.通过受试者工作特征(Receiver Operating Characteristic,ROC)曲线分析单能级40 keV图像、能谱曲线和有效原子序数对于胆囊内阴性结石与胆汁的诊断效能.结果 在40 keV时,阴性胆囊结石的有效原子序数为6.12±0.37,胆汁的有效原子序数为7.45±0.41,差异有统计学意义(P<0.05);阴性胆囊结石CT值为(-40.12±12.67)HU,胆汁CT值为(5.78±14.89)HU,差异有统计学意义(P<0.05).阴性胆囊结石的能谱曲线斜率为-1.58±0.39,胆汁的能谱曲线斜率为0.27±0.12,差异有统计学意义(P<0.05).ROC曲线显示单能级40 keV图像、能谱曲线和原子序数图的曲线下面积分别为0.940、0.951和0.974,敏感度和特异性分别为88.89%和84.21%、92.31%和91.12%、100%和96.11%.结论 能谱CT多参数成像有助于早期发现胆囊结石,指导临床治疗决策,减少误诊和漏诊的风险,对患者的治疗和预后具有积极影响.

Objective To explore the value of spectral CT's single-energy imaging,spectral curve,and atomic number in the diagnosis of negative gallbladder stones.Methods Imaging data of 76 patients with suspected negative gallbladder stones were retrospectively collected,and all patients underwent cholecystectomy,with surgical results as the reference standard.Differences in 40 keV single-energy images,spectral curve slopes,and effective atomic numbers between negative gallbladder stones and bile were compared.The diagnostic efficacy of 40 keV single-energy images,spectral curves,and effective atomic numbers for distinguishing negative gallbladder stones from bile was analyzed using receiver operating characteristic(ROC)curves.Results At 40 keV,the effective atomic number of negative gallbladder stones was 6.12±0.37,while that of bile was 7.45±0.41,with a statistically significant difference(P<0.05).The CT value of negative gallbladder stones was(-40.12±12.67)HU,and that of bile was(5.78±14.89)HU,showing a statistically significant difference(P<0.05).The spectral curve slope of negative gallbladder stones was-1.58±0.39,compared with 0.27±0.12 for bile,with a statistically significant difference(P<0.05).ROC curve analysis showed that the areas under the curve of 40 keV single-energy images,spectral curves,and atomic number maps were 0.940,0.951,and 0.974,respectively,with sensitivities and specificities of 88.89%and 84.21%,92.31%and 91.12%,100%and 96.11%.Conclusion Spectral CT multiparametric imaging is helpful for early detection of gallbladder stones,guides clinical treatment decisions,reduces the risk of misdiagnosis and missed diagnosis,and has a positive impact on patient treatment and prognosis.

陈宗桂;李禹睿;钟志明;魏宁宁;张英俊

湖南医药学院 医学院,湖南 怀化 418000湖南医药学院 医学院,湖南 怀化 418000广西国际壮医医院 放射科,广西 南宁 530201湖南医药学院 医学院,湖南 怀化 418000湖南医药学院 医学院,湖南 怀化 418000

医药卫生

阴性胆囊结石能谱CT成像能谱曲线原子序数图虚拟单能量多参数成像

negative gallbladder stonesspectral CT imagingspectral curveatomic number mapvirtual single energymultiparametric imaging

《中国医疗设备》 2025 (9)

129-133,5

湖南省自然科学基金青年项目(2021JJ40385)湖南省教育厅一般项目(22C1183).

10.3969/j.issn.1674-1633.20242039

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