磁共振定量分析在早期膝关节炎软骨损伤情况中的研究进展OA

Knee Osteoarthritis(KOA)is an irreversible degenerative disease.In the early stage,it mainly involves the cartilage,and the pathological changes of cartilage occur much earlier than its morphological changes,making conventional magnetic resonance imaging of limited value.Magnetic resonance(MR)quantitative analysis enables quantitative assessment of early articular cartilage damage based on changes in different components of the cartilage.This paper systematically reviewed the current application status of various MR quantitative imaging methods in the early diagnosis of KOA,and analyzed the advantages and limitations of different MR quantitative methods in terms of sensitivity,specificity,imaging time,and hardware requirements.It is pointed out that improvements should be made in shortening data acquisition time,improving image quality,and reducing radiofrequency energy accumulation.Additionally,the development direction of integrating this field with artificial intelligence was prospected,aiming to provide references for early intervention and efficacy monitoring of KOA.