首页|期刊导航|中国医疗设备|不同视觉信息脑力负荷任务下的脑皮层功能连接特性分析

不同视觉信息脑力负荷任务下的脑皮层功能连接特性分析OA

Analysis of the Functional Connectivity Characteristics of the Cerebral Cortex Under Different Visual Information Mental Load Tasks

中文摘要英文摘要

目的 研究不同类型视觉信息的脑力负荷任务下,大脑皮层功能连接特性随脑力负荷变化的规律.方法 基于N-Back范式设计不同信息类型、不同难度的脑力负荷任务,任务执行时同步收集18名受试者的60通道脑电信号;基于sLORETA方法对头皮脑电信号进行源定位,并基于皮尔逊相关方法构建Theta和Alpha频带皮层脑电功能网络,采用统计分析方法筛选各任务下随脑力负荷均呈显著变化的网络节点与全局指标.结果 4个任务中,2个频带共6个节点的度值、4组功能连接的连接强度随脑力负荷的变化而变化,且差异有统计学意义(P<0.05);随着脑力负荷增大,Theta频带网络平均特征路径长度由(2.8427±0.0083)减小到(2.7751±0.0051),而平均聚类系数和全局效率则分别由(0.3384±0.0018)、(0.4232±0.0015)增大到(0.3620±0.0020)、(0.4432±0.0017).结论 脑皮层功能连接指标可有效表征不同视觉信息记忆任务下脑力负荷的变化情况.

Objective To study the variation pattern of the functional connectivity characteristics of the cerebral cortex with mental load under different types of visual information mental load tasks.Methods Based on the N-Back paradigm,brain-load tasks of different information types and difficulties were designed.During the task execution,60-channel electroencephalogram(EEG)signals of 18 subjects were synchronously collected.The source location of scalp electroencephalogram signals was carried out based on the sLORETA method,and the Theta and Alpha band cortical EEG functional networks were constructed based on the Pearson correlation method.Statistical analysis methods were used to screen the network nodes and global indicators that showed significant changes with the mental load under each task.Results Among the 4 tasks,the degree values of 6 nodes in 2 frequency bands and the connection strengths of 4 groups of functional connections changed with the variation of mental load,and the differences were statistically significant(P<0.05).With the increase of mental load,the average characteristic path length of the Theta frequency band network decreased from(2.8427±0.0083)to(2.7751±0.0051).The average clustering coefficient and global efficiency increased from(0.3384±0.0018)and(0.4232±0.0015)to(0.3620±0.0020)and(0.4432±0.0017),respectively.Conclusion Functional connectivity indicators of the cerebral cortex can effectively represent the changes in mental load under different visual information memory tasks.

关凯

中国电子科技集团公司信息科学研究院,北京 100041

医药卫生

脑力负荷视觉信息N-Back脑电源定位功能连接特性分析

mental loadvisual informationN-Backelectroencephalogramsource localizationfunctional connectivity characteristics analysis

《中国医疗设备》 2025 (8)

43-51,9

10.3969/j.issn.1674-1633.20240317

评论