基于痰湿体质的高尿酸血症防治策略研究进展OA
Research progress on the prevention and treatment strategy of hyperuricemia based on phlegm-dampness constitution
医学探究健康与疾病关系,中医"治未病"思想受重视.中医体质学作用重要,含辨体防病等层次.现代用"九体分类法",高尿酸血症(HUA)与中医体质相关性研究显示痰湿体质常见.从"体病相关"理论看,痰湿体质是HUA发病及病情发展影响因素.基因层面,其有代谢紊乱风险且与HUA遗传相关;胰岛素抵抗与之密切相关;有慢性低度炎症表现,可能加重HUA炎症;存在免疫细胞紊乱,推测加剧HUA人群免疫失衡;肠道菌群紊乱或是易患HUA机制.中医治HUA重健脾祛湿,调理痰湿体质是防控关键,可为"治未病"及HUA防治助力.
Medicine explores the relationship between health and disease,and the idea of"treating the disease before it occurs"in Chinese medicine is emphasized.The role of TCM somatology is important,containing levels such as body identification and disease prevention.In modern times,the correlation between hyperuricemia(HUA)and the TCM constitution using the"Nine Body Classification Method"shows that phlegm-dampness is common.From the theory of"body-disease correlation",phlegm-dampness is a factor influencing the onset and progression of HUA.At the genetic level,it is at risk of metabolic disorders and is genetically related to HUA,insulin resistance is closely related to it;chronic low-grade inflammation may exacerbate inflammation in HUA,immune cell disorders may exacerbate the immune imbalance in HUA,and disturbances in the intestinal flora may be a mechanism of HUA susceptibility.The Chinese medicine treatment of HUA emphasizes strengthening the spleen and dispelling dampness,and regulating phlegm-dampness is the key to preventing and controlling HUA,which can be helpful for"treating the disease before it occurs"and HUA prevention and treatment.
曹凤娇;易文明;吴梦玮;高傲;侯秀娟
北京中医药大学东方医院治未病中心,北京 100078北京中医药大学东方医院治未病中心,北京 100078北京中医药大学东方医院治未病中心,北京 100078北京中医药大学东方医院治未病中心,北京 100078北京中医药大学东方医院风湿科,北京 100078
医药卫生
高尿酸血症中医体质痰湿体质肠道菌群免疫紊乱
HyperuricemiaTCM constitutionPhlegm-dampness constitutionGut microbiotaImmune imbalance
《中国医药科学》 2025 (13)
42-45,4
国家中医药管理局"十二五"重点专科建设项目.
评论