不同螺纹种植体即刻种植即刻负荷的比格犬体内实验OA
In vivo experiment of repairing mandibular first molar with different thread implants under immediate load in Beagle dogs
目的 探讨2 种不同螺纹设计的种植体在下颌磨牙区即刻负荷时对种植体和种植体周围骨界面生物学分布的影响及其骨结合情况.方法 采用比格犬建立即刻种植即刻负荷模型,通过组织学实验检测双螺纹锥柱状种植体(BLX)和锥柱状种植体(BLT)2 种种植体的植入精度、种植体稳定系数(ISQ)及骨结合情况,评估其在体内的稳定性和骨结合情况.结果 BLX种植体和BLT种植体在植入点总偏差、根尖点总偏差和角度偏差方面差异无统计学意义(P>0.05);比较术后3 个月双螺纹锥柱状种植体和锥柱状种植体各个方向的ISQ值,差异无统计学意义(P>0.05);术后3 个月组织学观察,发现锥柱状种植体的骨-种植体接触(BIC)和骨体积/组织体积(BV/TV)值均显著小于双螺纹锥柱状种植体(P<0.05).结论 双螺纹锥柱状设计的种植体在即刻种植即刻负荷时具有较高的初始稳定性和骨结合率,提示临床上磨牙区即刻种植即刻负荷时可优先考虑使用双螺纹锥柱状种植体.
Objective To investigate the effect of two kinds of implants with different thread designs on the biological distribution of the implant and the bone interface surrounding the mandibular molar area under immediate load.Methods Beagle dogs were employed for the immediate implantation and immediate loading model.The accuracy,implant stability quotient(ISQ),and osseointegration of the two implants were evaluated by histological analysis,and the stability and osseointegration of the two implants were evaluated in vivo.Results There were no significant differences in total error of implant point,total error of apical point,and angle error between conical cylindrical implants and double-threaded conical cylindrical implants(P>0.05).There was no significant difference in ISQ values of the two types of implants in all directions 3 months after operation(P>0.05).Histological observation at 3 months after surgery showed that conical cylindrical implants'BIC and BV/TV values were significantly lower than those of double-threaded conical cylindrical implants(P<0.05).Conclusion The double-threaded cone-column design of double-threaded conical cylindrical implants has higher initial stability and bone binding rate during immediate implantation and immediate loading,suggesting that double-threaded conical cylindrical implants should be given priority when immediate implantation and immediate loading in the molar area.
李昕茹;曹泽鹏;刘一伯;韩泽奎;周立波
黑龙江省口腔生物材料与临床应用重点实验室 佳木斯大学口腔医学工程实验中心佳木斯大学附属口腔医院 154002黑龙江省口腔生物材料与临床应用重点实验室 佳木斯大学口腔医学工程实验中心佳木斯大学附属口腔医院 154002黑龙江省口腔生物材料与临床应用重点实验室 佳木斯大学口腔医学工程实验中心佳木斯大学附属口腔医院 154002黑龙江省口腔生物材料与临床应用重点实验室 佳木斯大学口腔医学工程实验中心佳木斯大学附属口腔医院 154002黑龙江省口腔生物材料与临床应用重点实验室 佳木斯大学口腔医学工程实验中心佳木斯大学附属口腔医院 154002
即刻种植即刻负荷螺纹设计种植体稳定系数骨结合率
Immediate implant placement and immediate loadingThread designImplant stability quotientOsseointegration rate
《中国口腔种植学杂志》 2025 (3)
255-261,7
中国牙病防治基金会口腔种植科学研究专项基金(COHF ZZZX202410)黑龙江省高等教育教学改革项目(SJGZ20220124) Scientific Research Projects for Oral Implantology of China Oral Health Foundation(COHF ZZZX202410)Heilongjiang Province Higher Education Teaching Reform Project(SJGZ20220124)
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