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接触式DCT实验装置与仿体实验设计OA

Design of Contact-DCT Experimental Device and Phantom Experiment

中文摘要英文摘要

目的 为解决大面积接触式漫射相关层析成像(Diffuse Correlation Tomography,DCT)设备由于需要大规模光源-探测(Source-Detector,S-D)阵列完成数据采集导致设备成本升高的问题.方法 研究提出采用光开关阵列将1组S-D时分复用为8组,共覆盖8 cm×8 cm目标组织.每组长短距离的S-D交叉分布形成同心圆结构,利用其对称性和对等性,保证体素获得光子的均衡性,同时扩大探测面积和深度.结果 利用该低成本DCT设备,仿体"十字型"异质物重建位置精确,形态基本完整,重建图像第二层(深度0.5~1.0 cm)的对比度为0.75;"管状"异质物的对比度与流速呈良好的线性关系,重建位置精确,形态完整;临床袖带加压测试实验自然状态的血流指数约为加压状态的10倍,且3D图像和图像标准差也显示自然状态的血运更丰富.结论 该接触式DCT设备对形态各异的异质物检测能力较强,可作为一种新的检测手段检测与血流灌注异常相关的疾病.

Objective To solve the problem of increased equipment cost caused by the need for large-scale source-detector(S-D)arrays to complete data acquisition in large-area contact diffuse correlation tomography(DCT)equipment.Methods An optical switch array was used to time-division multiplexing one group of S-D into eight groups,covering a total of 8 cm×8 cm target tissue.Each long and short distance S-D cross distribution formed a concentric circle structure.By taking advantage of its symmetry and equivalence,the balance of photons obtained by voxel was guaranteed,while the detection area and depth were expanded.Results By using this low-cost DCT equipment,the reconstructed position of the Phantom"cross-shaped"heterogeneous object was accurate,the shape was basically complete,and the contrast of the second layer(depth 0.5-1.0 cm)of the reconstructed image was 0.75.The contrast of the"tubular"heterogeneous substances showed a good linear relationship with the flow velocity,with precise reconstruction positions and complete morphology.The blood flow index in the natural state of the clinical cuffcompression test experiment was approximately 10 times that in the pressurized state,and the 3D images and image standard deviations also showed that the blood supply in the natural state was more abundant.Conclusion This contact-type DCT equipment has a strong detection ability for heterogeneous substances of various shapes and can be used as a new detection method to detect diseases related to abnormal blood perfusion.

晏文;刘凯;尚禹;张晓娟

太原师范学院 计算机科学与技术学院,山西 太原 030619太原师范学院 计算机科学与技术学院,山西 太原 030619中北大学 省部共建动态测试技术国家重点实验室,山西 太原 030051太原工业学院 电子工程系,山西 太原 030008

医药卫生

漫射相关断层成像(DCT)光源-探测器分布光开关阵列仿体实验N阶线性算法Bregman分裂算法

diffuse correlation tomography(DCT)light source-detector distributionoptical switch arrayphantom experimentN-order linear algorithmBregman splitting algorithm

《中国医疗设备》 2025 (6)

29-36,8

山西省基础研究计划项目(202203021212325202203021211100)山西省留学回国人员科技活动择优资助项目(2022-0034)山西省回国留学人员科研资助项目(2021-154)太原工业学院引进人才科研资助项目(20220401)太原工业学院第五届青年(后备)学科带头人项目(20231202).

10.3969/j.issn.1674-1633.20241369

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