Salamanders aid research into mechanisms of non-canonical organ regeneration for clinical applicationsOA
Salamanders possess remarkable regenerative capacities for organ regenera-tion among tetrapod vertebrates.Previous research has primarily focused on studying the regeneration of canonical tissues or organs such as limbs,tail,brain,spinal cord,heart,and lens.The advancements made in these areas have broader implications for understanding regeneration and developing thera-peutic approaches for these organs,not only in salamanders but also in other vertebrates.In recent years,there has been an increasing interest in studying the regeneration of non-canonical organs in salamanders,such as the liver,lungs,kidneys,and pancreas.This diversification of research has opened up new avenues and provided potential solutions to challenging clinical problems.This review aims to summarize the progress made in the field of non-canonical organ regeneration in salamanders and provides an outlook on future research directions.
Binxu Yin;Xiao Cui;Yanmei Liu;Ji-Feng Fei
Department of Pharmacy and Central Laboratory,Sichuan Academy of Medical Sciences Sichuan Provincial People's Hospital,University of Electronic Science and Technology of China,Chengdu,China||Department of Pathology,Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou,China||The Innovation Centre of Ministry of Education for Development and Diseases,School of Medicine,South China University of Technology,Guangzhou,China||School of Basic Medical Sciences,Southern Medical University,Guangzhou,ChinaDepartment of Pathology,Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou,China||The Innovation Centre of Ministry of Education for Development and Diseases,School of Medicine,South China University of Technology,Guangzhou,China||School of Basic Medical Sciences,Southern Medical University,Guangzhou,ChinaKey Laboratory of Brain,Cognition and Education Sciences,Ministry of Education,Institute for Brain Research and Rehabilitation,Guangdong Key Laboratory of Mental Health and Cognitive Science,South China Normal University,Guangzhou,ChinaDepartment of Pathology,Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou,China||The Innovation Centre of Ministry of Education for Development and Diseases,School of Medicine,South China University of Technology,Guangzhou,China||School of Basic Medical Sciences,Southern Medical University,Guangzhou,China
kidneyliverlungpancreasregenerationsalamander
kidneyliverlungpancreasregenerationsalamander
《医学前沿（英文）》 2024 (2)
101-111,11
National Natural Science Foundation of China,Grant/Award Numbers:31970782,32070819,92268114High-level Hospital Construction Project of Guangdong Provincial People's Hospital,Grant/Award Numbers:DFJHBF202103,KJ012021012BGI,Grant/Award Number:BGIRSZ20210002Key-Area Research and Development Program of Guangdong Province,Grant/Award Number:2019B030335001
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