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Take the Road Less Traveled:Pulmonary Artery Banding to Rescue the Children''s Failing HeartOA

中文摘要

Pediatric dilated cardiomyopathy(DCM)isa leading cause of heart failure in children,presenting.significant therapeutic challenges due to the limited efficacy of pharmacological treatments,thescarcity of donor hearts for transplantation,and the high costs associated with ventricular assistdevices.Also,the economic burden of DCM medical management is a critical topic for world wide.In this context,the development of a safe,effective,and economically viable surgical intervention isof paramount importance.A recent study published in CongenitalHeart Disease,titled"CardiacRehabilitation by Pulmonary Artery Banding after Induced Dilated Candiomyopathy:A Pilot Studyon a Rodent Model",represents a significant advancement in this field.This study evaluated thefeasibility and therapeutic potential of pulmonary artery banding(PAB)in a drug-induced DMrodent model,providing critical preclinical evidence to support its clinical translation[1].

Chenyu Jiang;Hao Zhang

Department of Cardiofthoracic Surgery,Shanghai Children''s Medical Center,Shanghai Jiao Tong University School of Medicine,Shanghai,200127,ChinaDepartment of Cardiofthoracic Surgery,Shanghai Children''s Medical Center,Shanghai Jiao Tong University School of Medicine,Shanghai,200127,China

医药卫生

heart failurepediatric dilated cardiomyopathy dcm isaventricular assistdevicesalsothepulmonary artery bandingpediatric dilated cardiomyopathypharmacological treatmentsthescarcitycardiac rehabilitationsurgical intervention

《Congenital Heart Disease》 2025 (2)

P.129-131,3

10.32604/chd.2025.064155

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