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Insights into morphine:Extraction,structural characterization,and pharmacological propertiesOA

中文摘要

Morphine is a potent opioid medicine utilized for the management of moderate to severe pain,particularly in palliative care,post-surgical recovery,and cancer treatment.But,it carries risks of addiction liability and respiratory depression.Thus,aim of the review was designed to insights into morphine:extraction,structural characterization,and pharmacological properties.A literature survey on scientific journals,books as well as electronic sources was performed for the content.This review delves into the multifaceted aspects of morphine,one of the most well-known opiate analgesics,focusing on its extraction,structural characterization,and pharmacological properties.The pharmacological profile of morphine is critically examined,highlighting its mechanisms of action,including its interactions with opioid receptors,and the resulting physiological effects.Also,the therapeutic applications of morphine is discussed in pain management,its potential for addiction,and the emergence of tolerance.By synthesizing current knowledge,this review provides a comprehensive understanding of morphine’s significance in medicine and its implications for future pharmacological developments.

Javeriya Ahrar;Md.Nematullah;Md.Azizur Rahman

Department of Pharmacy,Faculty of Pharmacy,Integral University,Lucknow 226026,Uttar Pradesh,IndiaDepartment of Pharmacy,Faculty of Pharmacy,Integral University,Lucknow 226026,Uttar Pradesh,IndiaDepartment of Pharmacy,Faculty of Pharmacy,Integral University,Lucknow 226026,Uttar Pradesh,India

医药卫生

MorphineIsolationPurificationSynthesisPharmacologyBiological activity

《LabMed Discovery》 2025 (1)

P.48-54,7

10.1016/j.lmd.2025.100043

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