Inhibition of P2X7R alleviates neuroinflammation and brain edema after traumatic brain injury by suppressing the NF-κB/NLRP3 inflammasome pathwayOA
Inhibition of P2X7R alleviates neuroinflammation and brain edema after traumatic brain injury by suppressing the NF-κB/NLRP3 inflammasome pathway
Bingyan Tao;Jun Zhang;Jie Pei;Hao Li;Guochao Yang;Xudong Shi;Zehan Zhang;Hui Wang;Zhou Zheng;Yuyang Liu
Department of Neurosurgery,The First Medical Centre,Chinese PLA General Hospital,Beijing 100853,China||Department of Neurosurgery,961th Hospital of Joint Logistics Support Force,Qiqihar 161000,Heilongjiang,China||Medical School of Chinese PLA,Beijing 100853,ChinaDepartment of Neurosurgery,The First Medical Centre,Chinese PLA General Hospital,Beijing 100853,ChinaInstitute of Military Cognition and Brain Sciences,Beijing 100850,ChinaDepartment of Neurobiology,Beijing Institute of Basic Medical Sciences,Beijing 100850,ChinaMinistry of Education(MOE)Key Laboratory of Model Animal for Disease Study,Model Animal Research Center,Jiangsu Key Laboratory of Molecular Medicine,Medical School,Nanjing University,Nanjing 210061,Jiangsu,ChinaDepartment of Neurosurgery,The First Medical Centre,Chinese PLA General Hospital,Beijing 100853,China||Medical School of Chinese PLA,Beijing 100853,ChinaDepartment of Neurosurgery,PLA Air Force Hospital of Southern Theatre Command,Guangzhou 510602,Guangdong,ChinaDepartment of Experimental Pathology,Beijing Institute of Radiation Medicine,Beijing 100850,ChinaDepartment of Emergency,920th Hospital of Joint Logistics Support Force,Kunming 650032,Yunnan,ChinaMedical School of Chinese PLA,Beijing 100853,China||Department of Neurosurgery,920th Hospital of Joint Logistics Support Force,Kunming 650032,Yunnan,China||Chinese PLA Spinal Cord Injury Treatment Center,Kunming 650032,Yunnan,China
Traumatic brain injuryNeuroinflammationBrain edemaP2X7RNF-κBNLRP3
Traumatic brain injuryNeuroinflammationBrain edemaP2X7RNF-κBNLRP3
《神经修复学（英文）》 2024 (2)
87-97,11
This research was funded by the National Natural Science Foundation of China(No.81971167).
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