计算机辅助手术系统在儿童节细胞神经母细胞瘤手术中的应用OA北大核心

Objective To explore the clinical application value and significance of computer-assisted surgical system for gangliocytic neuroblastoma(GNB)in children.Methods From January 2013 to December 2023,the clinical data of 33 surgical GNB children were retrospectively reviewed.According to whether or not using Hisense CAS for 3D preoperative reconstruction,they were assigned into two groups of two-dimensional CT reconstruction(n=17)and three-dimensional CT reconstruction(n=16).Mann-Whitney U,x2 and Fisher ex-act tests were utilized for examining the inter-group differences in operative duration,intraoperative volume of blood loss,postoperative hospitalization stay and recurrence.Results Operative duration was shorter in three-dimensional CT reconstruction group than that in two-dimensional CT group[(131.40±41.60)vs.(169.39±57.82)].Median intraoperative volume of blood loss was less in three-dimensional CT reconstruction group than that in two-dimensional CT reconstruction group[20(10.0-27.5)vs.30(20.0-60.0)mL].Postoperative indwelling time of drainage tube was shorter than that of two-dimensional CT reconstruction group(P＜0.05).Follow-ups were conducted until April 2024.In two-dimensional CT reconstruction group,there were postoperative recurrence(n=3)and death(n=1).It was probably correlated with an incomplete resection of multiple tumor metastases.Intraoperative status of three-dimensional CT reconstruction group was highly consistent with that of preoperative three-dimensional CT reconstruction.Tumors were completely removed without any residue.There was no recurrence or metastasis.Conclusions Through preoperative imaging of ganglioneuroblastoma,3D reconstruc-tion of computer-assisted surgery system assists in designing and optimizing surgical protocols so as to enable op-erations to be more accurate and safe.It has important guiding significance for managing pediatric GNB.