儿童Ⅰ型神经纤维瘤病脊柱侧弯的诊治要点OA北大核心

Children of type 1 neurofibromatosis may present with a wide range of symptoms,including café au lait spots,plexiform neurofibromas and skeletal system deformities.Among them,scoliosis is the most common skeletal deformity.Children with NF1 scoliosis often have nutritional deficiency-type changes in spinal bones,leading to early onset and rapid progression of scoliosis,causing deformity of appearance and affecting normal growth and development of spine.Thus early intervention is necessary.Based on the location,type,de-gree of scoliosis,and patient age and growth potential,appropriate treatments may be selected.In addition to treating scoliosis,attention should also be paid to managing concomitant deformities and preventing complica-tions.For overall management of NF1,multidisciplinary treatment is needed to provide standardized,individual-ized and meticulous treatment.