黏性骨在骨再生中的应用研究OA

The high concentrations of growth factors within platelets have been proven to promote cell migration,proliferation,and angiogenesis during the regeneration process.Multiple efforts have been exerted to blend them with bone substitute materials,to fabricate"sticky bone"for easier manipulation by surgeons.While autologous and allogeneic bone grafts are limited by donor site availability and biocompatibility issues,synthetic bone grafts exhibit significant advantages in terms of biocompatibility.The integration of growth factors into these porous synthetic grafts can effectively stimulate cell growth and differentiation,thereby enhancing osteogenic potential.This paper reviews the research and advancements in sticky bone for bone regeneration,elaborating on the fabrication and characterization of sticky bone materials.Moreover,it also highlights the promising outcomes and benefits of sticky bone in bone defect regeneration,substantiated by clinical data from both domestic and international studies.