P2X7 receptors and multiple sclerosis: A potential biomarker and therapeutic target?OA
Multiple sclerosis(MS) is a chronic, autoimmune and neuroinflammatory disease of the central nervous system(CNS) with a neurodegenerative component, characterized by demyelination and degeneration of nerve fibers. It affects mainly young adults(aged 20 to 45 years) and its causes are still unknown, but it is thought that external factors such as viruses and environmental factors trigger the disease in people with a genetic susceptibility.
Cristina Agliardi;Franca Rosa Guerini;Mario Clerici
IRCCS Fondazione Don Carlo Gnocchi ONLUS,Milan,ItalyIRCCS Fondazione Don Carlo Gnocchi ONLUS,Milan,ItalyIRCCS Fondazione Don Carlo Gnocchi ONLUS,Milan,Italy Department of Pathophysiology and Transplantation,University of Milan,Milan,Italy
医药卫生
sclerosisdegenerationtherapeutic
《Neural Regeneration Research》 2026 (1)
P.318-319,2
supported by Italian Ministry of Health Ricerca Corrente [RC 2023] and RF-2016-02361294supported by#NEXTGENERATIONEU (NGEU)funded by the Ministry of University and Research (MUR)National Recovery and Resilience Plan (NRRP)project MNESYS (PE0000006)–A Multiscale integrated approach to the study of the nervous system in health and disease (DN. 1553 11.10.2022)(to FRG)partially supported by a grant from Fondazione Romeo ed Enrica Invernizzi (to FRG)。
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