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Spinal cord injury–associated disruption of the autonomic immune control:Does biological sex matter?OA

中文摘要

The impact of spinal cord injury(SCI)on the immune system is increasingly recognized in a field traditionally focused on motor impairments.SCI can seriously affect the immune system by progressively disrupting the regulatory mechanisms that control immune responses.This dysregulation varies widely among patients and can evolve over time,ranging from systemic inflammatory responses to immunosuppression,greatly contributing to the morbidity and mortality of individuals with SCI(Bao et al.,2011;Brennan et al.,2024).

Sara Rito-Fernandes;António J.Salgado;Nuno A.Silva;Susana Monteiro

Life and Health Sciences Research Institute(ICVS),School of Medicine,University of Minho,Braga,Portugal ICVS/3B’s Associate Lab,PT Government Associated Lab,Braga/Guimarães,PortugalLife and Health Sciences Research Institute(ICVS),School of Medicine,University of Minho,Braga,Portugal ICVS/3B’s Associate Lab,PT Government Associated Lab,Braga/Guimarães,PortugalLife and Health Sciences Research Institute(ICVS),School of Medicine,University of Minho,Braga,Portugal ICVS/3B’s Associate Lab,PT Government Associated Lab,Braga/Guimarães,PortugalLife and Health Sciences Research Institute(ICVS),School of Medicine,University of Minho,Braga,Portugal ICVS/3B’s Associate Lab,PT Government Associated Lab,Braga/Guimarães,Portugal

医药卫生

mortalitySpinal

《Neural Regeneration Research》 2026 (1)

P.298-299,2

funded by the Santa Casa Neuroscience Awards—Prize Melo e Castro for Spinal Cord Injury Research(MC-18-2021)(to AJS and NAS)by the Wings for Life Spinal Cord Research Foundation(WFL-PT-14/23)(to NAS)funded by national funds through the Foundation for Science and Technology(FCT)—projects UIDB/50026/2020,UIDP/50026/2020,and EXPL/MED-PAT/0931/2021-http://doi.org/10.54499/EXPL/MED PAT/0931/2021supported by the Norte Portugal Regional Operational Programme(NORTE 2020)under the PORTUGAL 2020 Partnership Agreement through the European Regional Development Fund(ERDF)(to SM)the support given by the Portuguese Foundation of Science and Technology to SM(CEECIND/01902/2017-Doi:10.54499/CEECIND/01902/2017/CP1458/CT0024),and NAS(CEECIND/04794/2007)。

10.4103/NRR.NRR-D-24-01078

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