Review on the research progress into the traditional Chinese medicinal Jing Fang granules:chemical composition,pharmacological effects and clinical applicationsOA
Jing Fang granules(JFG)are a modern Chinese medicinal formulation derived from Jing Fang Defeating Toxin San(JFDS).JFG primarily contains bioactive compounds such as flavonoids/flavonoid glycosides,coumarins and other components,which have various activities:anti-inflammatory,immune system regulation,antiviral,anti-aging,detoxification,and protection of the liver,lungs,and kidneys.JFG has broad potential therapeutic applications.The mechanisms of JFG’s actions are primarily associated with signaling pathways such as TLR4/NF-κB,PI3K/AKT,and MAPK.This article reviews the research progress on JFG,including chemical composition,pharmacologic effects,mechanism of action,safety,clinical application,etc.,serving as a foundation for future research and clinical applications.
Rui Zhao;Tai-Li Zhao;Hong-Hua Li;Pei-Pei Zhao;Meng-Meng Wang;Yi-Wei Meng;Jing-Li Ren;Xin Yin;Jing-Chun Yao
Biology Institute,Qilu University of Technology(Shandong Academy of Sciences),Jinan 250103,ChinaBiology Institute,Qilu University of Technology(Shandong Academy of Sciences),Jinan 250103,ChinaState Key Laboratory of Generic Manufacture Technology of Chinese Traditional Medicine,Lunan Pharmaceutical Group Co.,Ltd.,Linyi 276005,ChinaBiology Institute,Qilu University of Technology(Shandong Academy of Sciences),Jinan 250103,ChinaBiology Institute,Qilu University of Technology(Shandong Academy of Sciences),Jinan 250103,ChinaBiology Institute,Qilu University of Technology(Shandong Academy of Sciences),Jinan 250103,ChinaBiology Institute,Qilu University of Technology(Shandong Academy of Sciences),Jinan 250103,ChinaBiology Institute,Qilu University of Technology(Shandong Academy of Sciences),Jinan 250103,ChinaState Key Laboratory of Generic Manufacture Technology of Chinese Traditional Medicine,Lunan Pharmaceutical Group Co.,Ltd.,Linyi 276005,China
医药卫生
chemical compositionclinical applicationJing Fang granulespharmacological effecttraditional Chinese herbal formula
《Integrative Medicine Discovery》 2025 (6)
P.1-13,13
supported by the Key R&D Program of Shandong Province,China(No.2024TZXD067,2022SFGC0105)Natural Science Foundation of Shandong Province(No.ZR2023QB021)Young Taishan Scholarship to Xuekui Xia(No.tsqn202103100)Jinan Talent Project for Universities(No.2021GXRC062,202228088)Key innovation Project and Science,Education and Industry Integration Innovation Pilot Project of Qilu University of Technology(Shandong Academy of Sciences)(No.2022JBZ01-06,2024ZDZX03,2023RCKY214).
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