首页|期刊导航|中华医学杂志(英文版)|Heterotopic ossification:Current developments and emerging potential therapies

Heterotopic ossification:Current developments and emerging potential therapiesOACSCDCSTPCD

Heterotopic ossification:Current developments and emerging potential therapies

Mingjian Bei;Xinbao Wu;Qiyong Cao;Chunpeng Zhao;Yaping Xiao;Yimin Chen;Honghu Xiao;Xu Sun;Faming Tian;Minghui Yang

Department of Orthopedic Surgery,Beijing Jishuitan Hospital Affiliated to Capital Medical University,Beijing 100035,ChinaDepartment of Orthopedic Surgery,Beijing Jishuitan Hospital Affiliated to Capital Medical University,Beijing 100035,China||Beijing Research Institute of Traumatology and Orthopaedics,Beijing 100035,ChinaDepartment of Orthopedic Surgery,Beijing Jishuitan Hospital Affiliated to Capital Medical University,Beijing 100035,ChinaDepartment of Orthopedic Surgery,Beijing Jishuitan Hospital Affiliated to Capital Medical University,Beijing 100035,ChinaDepartment of Orthopedic Surgery,Wuhan Third Hospital,Tongren Hospital of Wuhan University,Wuhan,Hubei 430000,ChinaDepartment of Orthopedic Surgery,Beijing Jishuitan Hospital Affiliated to Capital Medical University,Beijing 100035,ChinaDepartment of Orthopedic Surgery,Beijing Jishuitan Hospital Affiliated to Capital Medical University,Beijing 100035,ChinaDepartment of Orthopedic Surgery,Beijing Jishuitan Hospital Affiliated to Capital Medical University,Beijing 100035,ChinaSchool Of Public Health,North China University of Science and Technology,Tangshan,Hebei 063210,ChinaDepartment of Orthopedic Surgery,Beijing Jishuitan Hospital Affiliated to Capital Medical University,Beijing 100035,China

Heterotopic ossificationFibrodysplasia ossificans progressivaProgressive osseous heteroplasiaSignal transductionEndothelial-to-mesenchymal transitionHypoxia-inducible factor 1-alphaSmall molecule inhibitors

Heterotopic ossificationFibrodysplasia ossificans progressivaProgressive osseous heteroplasiaSignal transductionEndothelial-to-mesenchymal transitionHypoxia-inducible factor 1-alphaSmall molecule inhibitors

《中华医学杂志(英文版)》 2025 (4)

389-404,16

This work was supported by the grants from the Beijing Scholar Training ProgramBeijing Municipal Public Wel-fare Development and Reform Pilot Project for Medical Research Institutes(Nos.JYY2023-11,JYY2023-8)Bei-jingJSTResearchFunding(No.2023OSR-GCZX202205)Beijing Municipal Excellent Plan Empowerment Project(No.YC202301QX0029)Beijing postdoctoral research Funding(No.2023-zz-008),and National Key Research and Development(R&D)Plan(No.2022YFC2504304).

10.1097/CM9.0000000000003244

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