Role of silent mutations in KRAS-mutant tumorsOACSCDCSTPCD

作者：Jun Lu;Chao Zhou;Feng Pan;Hongyu Liu;Haohua Jiang;Hua Zhong;Baohui Han

作者单位：Department of Respiratory and Critical Care Medicine,Shanghai Chest Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China||Shanghai Institute of Thoracic Oncology,Shanghai Chest Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China||Translational Medical Research Platform for Thoracic Oncology,Shanghai Chest Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China||Department of Bio-bank,Shanghai Chest Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,ChinaDepartment of Respiratory and Critical Care Medicine,Shanghai Chest Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,ChinaDepartment of Respiratory and Critical Care Medicine,Shanghai Chest Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,ChinaDepartment of Respiratory and Critical Care Medicine,Shanghai Chest Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,ChinaDepartment of Respiratory and Critical Care Medicine,Shanghai Chest Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,ChinaDepartment of Respiratory and Critical Care Medicine,Shanghai Chest Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China||Translational Medical Research Platform for Thoracic Oncology,Shanghai Chest Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,ChinaDepartment of Respiratory and Critical Care Medicine,Shanghai Chest Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China||Shanghai Institute of Thoracic Oncology,Shanghai Chest Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China||Translational Medical Research Platform for Thoracic Oncology,Shanghai Chest Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China

中文关键词：KRAS mutationsSilent mutationTumorBiological characteristics

英文关键词：KRAS mutationsSilent mutationTumorBiological characteristics

刊名：《中华医学杂志（英文版）》 2025 (3)

页码/页数：278-288,11

基金：This work was supported by grants from the National Natural Science Foundation of China(Nos.82473102,82272913,82301980,and 82072573),National Mul-ti-disciplinary Treatment Project for Major Disease(No.2020NMDTP),Chinese Society of Clinical Oncology(Nos.Y-2019AZZD-0355 and Y-QL2019-012),and Shanghai Jiao Tong University(No.YG2021QN12).

DOI：10.1097/CM9.0000000000003405